Genotype | |||||
---|---|---|---|---|---|
Variable | CC | CT | TT | ||
(n = 23) 29.5 % | (n = 34) 43.6 % | (n = 21) 26.9 % | P value | ||
Age | years | 62.7 ± 6.9a | 63.6 ± 8.7 | 63.2 ± 8.7 | 0.920 |
Gender(Male/Female) | n | 11/12 | 10/29 | 10/11 | 0.261 |
Duration of hemodialysis | years | 28.0 (25.0-31.0)b | 31 (27.0-34.3) | 32.0 (28.5-35.0) | 0.276 |
Age at initiation of hemodialysis | years | 33.0 ± 7.3 | 32.7 ± 8.5 | 31.3 ± 8.2 | 0.760 |
Height | cm | 159.7 ± 9.1 | 155.7 ± 8.1 | 158.5 ± 7.5 | 0.170 |
Dry weight(DW) | kg | 50.0d (43.8-59.5) | 44.0e (39.1-50.9) | 52.6d (44.5-59.3) | 0.014* |
Body mass index(BMI) | kg/m2 | 20.2 ± 19.7 | 18.8 ± 2.8 | 20.5 ± 2.6 | 0.050 |
BMI<18.5 | n (%) | 7 (21.9 %)c | 19 (59.4 %) | 6 (18.8 %) | |
18.5≦BMI<25 | n (%) | 15 (35.7 %) | 14(33.3 %) | 13 (31.0 %) | |
25≦BMI | n (%) | 1 (25.0 %) | 1 (25.0 %) | 2 (50.0 %) | |
Bathel Index(BADL) | 90 (74-100) | 98 (84-100) | 85 (78-100) | 0.253 | |
BADL(independent/some help is necessary/with help) | n | 20/2/1 | 33/1/0 | 18/1/2 | <0.001* |
Geriatric nutrition risk index(GNRI) | 9489-90 | 9088-96 | 9491-99 | 0.200 | |
≧GNRI 91(without risk of malnutrition) | n(%) | 16 (34.8 %) | 15 (32.6 %) | 15 (32.6 %) | |
<GNRI 91(with risk of malnutrition) | n(%) | 7 (21.9 %) | 19 (59.4 %) | 6 (18.8 %) | |
Biochemical parameter | |||||
serum albumin (Alb) | g/dL | 3.7 ± 0.3 | 3.8 ± 0.3 | 3.7 ± 0.3 | 0.887 |
total protein (TP) | g/dL | 6.4d ± 0.3 | 6.6 ± 0.5 | 6.7e ± 0.5 | 0.045* |
blood urea nitrogen (BUN) | mg/dL | 63.8 ± 14 | 64.2 ± 6.6 | 67.6 ± 21.2 | 0.718 |
serum creatinine (Cr) | mg/dL | 10.8 ± 2.3 | 10.5 ± 2.2 | 10.8 ± 2.2 | 0.873 |
urea acid (UA) | mg/dL | 7.1 ± 1.3 | 6.9 ± 1.7 | 7.5 ± 1.5 | 0.341 |
serum sodium (Na) | mEq/L | 141 ± 2 | 140 ± 2.6 | 140 ± 2.9 | 0.847 |
serum potassium (K) | mEq/L | 5.1 ± 0.6 | 5.2 ± 0.7 | 5.1 ± 0.6 | 0.864 |
serum inorganic phosphorus (IP) | mg/dL | 5.7 ± 1.1 | 5.1 ± 1.2 | 5.6 ± 1.8 | 0.164 |
serum calcium (Ca) | mg/dL | 8.9 ± 0.7 | 9.3 ± 0.7 | 9 ± 0.6 | 0.096 |
Hemoglobin (Hb) | g/dL | 10.4 (9.1-11.5) | 10.3 (10.1-11.7) | 10.2 (9.5-11.1) | 0.789 |
Hematocrit (Ht) | % | 33.5 ± 4.3 | 32.9 ± 3.3 | 32.7 ± 2.9 | 0.164 |
serum folate | ng/mL | 4.7d (4.3-5.6) | 4.7d (3.8-6.0) | 3.9e (3.2-4.5) | 0.005* |
serum homocystein (Hcy) | μmol/L | 30.5d (25.2-37.6) | 25.1d (22.1-36.9) | 35.4e (27.3-58.3) | 0.029* |
serum vitaminB12 (VB12) | pmol/L | 545 (314-1200) | 630 (383-1328) | 456 (291-1463) | 0.763 |