Table 6 Laboratory parameters and vital signs of patients who continued LC use
Parameters | Start | 1 year after | 2 years after | 3 years after | 4 years after | 5 years after | 6 years after | 7 years after | 8 years after |
|---|---|---|---|---|---|---|---|---|---|
P (mg/dL) | 8.4 ± 1.3 | 5.0 ± 1.0*** | 5.4 ± 0.9*** | 5.1 ± 0.9*** | 5.7 ± 0.7*** | 5.7 ± 0.9*** | 5.5 ± 1.3*** | 6.0 ± 1.5*** | 5.5 ± 1.3*** |
Corrected Ca (mg/dL) | 9.2 ± 0.6 | 9.6 ± 0.6 | 9.6 ± 0.6 | 9.9 ± 0.8 | 9.2 ± 0.5 | 9.1 ± 0.6 | 9.2 ± 0.5 | 9.3 ± 0.5 | 9.3 ± 0.7 |
Intact PTH (pg/mL) | 334.6 ± 164.4 | 319.0 ± 185.3 | 353.4 ± 186.2 | 372.2 ± 228.2 | 218.9 ± 141.2** | 204.3 ± 136.4* | 225.2 ± 126.5* | 185.7 ± 111.6* | 200.9 ± 133.1* |
Na (mEq/L) | 138.9 ± 3.4 | 138.9 ± 2.3 | 139.1 ± 3.3 | 139.4 ± 2.3 | 138.3 ± 2.3 | 137.7 ± 2.5 | 138.4 ± 3.0 | 137.3 ± 3.0* | 138.8 ± 2.7 |
K (mEq/L) | 5.1 ± 0.8 | 5.1 ± 0.7 | 5.3 ± 0.6 | 5.2 ± 0.7 | 5.4 ± 0.6 | 5.1 ± 0.7 | 5.4 ± 0.7 | 5.3 ± 0.4 | 5.1 ± 0.7 |
Cl (mEq/L) | 100.4 ± 3.8 | 100.4 ± 3.0 | 100.8 ± 3.8 | 100.9 ± 3.4 | 101.9 ± 3.6 | 100.6 ± 3.5 | 101.1 ± 4.1 | 99.3 ± 2.9 | 101.2 ± 3.4 |
Glucose (mg/dL) | 129.0 ± 62.1 | 121.6 ± 47.7 | 121.4 ± 40.9 | 132.6 ± 73.1 | 139.3 ± 63.9 | 125.4 ± 38.2 | 132.2 ± 54.8 | 143.4 ± 103.2 | 108.1 ± 34.2 |
CRP (mg/dL) | 0.2 ± 0.2 | 0.2 ± 0.2 | 0.1 ± 0.1 | 0.2 ± 0.2 | 1.0 ± 1.7 | 0.8 ± 1.2 | 0.5 ± 0.9 | 0.7 ± 1.2 | 0.8 ± 1.2 |
RBC (×104/μL) | 331 ± 39 | 348 ± 35 | 344 ± 28 | 340 ± 35 | 356 ± 36 | 380 ± 82 | 360 ± 30 | 358 ± 41 | 362 ± 40 |
WBC (/μL) | 5800 ± 1229 | 6067 ± 1435 | 5856 ± 1574 | 6089 ± 1386 | 6533 ± 2061 | 6782 ± 2136 | 5911 ± 1945 | 6349 ± 2030 | 6126 ± 1841 |
Hb (g/dL) | 10.6 ± 1.0 | 10.9 ± 1.0 | 10.6 ± 0.9 | 10.6 ± 1.0 | 11.1 ± 0.8 | 11.1 ± 1.0 | 11.0 ± 0.8 | 10.4 ± 1.1 | 11.0 ± 1.0 |
Ht (%) | 32.0 ± 3.9 | 33.0 ± 2.7 | 32.4 ± 2.3 | 32.4 ± 3.2 | 34.3 ± 3.1 | 34.7 ± 3.1 | 34.2 ± 2.4 | 32.5 ± 3.1 | 33.8 ± 2.8 |
Plt (×104/μL) | 21.3 ± 4.3 | 21.5 ± 3.2 | 21.0 ± 4.2 | 21.4 ± 4.6 | 22.0 ± 6.2 | 22.3 ± 6.1 | 21.3 ± 5.8 | 23.1 ± 5.9 | 21.6 ± 6.9 |
Serum Alb (g/dL) | 4.1 ± 0.2 | 4.0 ± 0.2 | 4.1 ± 0.2 | 3.9 ± 0.3 | 3.9 ± 0.3 | 3.8 ± 0.2 | 3.9 ± 0.3 | 3.8 ± 0.2 | 3.6 ± 0.3 |
ALP (U/L) | 238.8 ± 129.5 | 290.1 ± 145.1 | 307.2 ± 166.1 | 333.9 ± 216.4 | 228.8 ± 83.4 | 244.6 ± 80.7 | 258.1 ± 102.5 | 254.9 ± 99.5 | 270.7 ± 107.9 |
LDH (IU/L) | 172.2 ± 33.4 | 165.4 ± 25.9* | 170.1 ± 26.8 | 172.2 ± 30.3 | 175.4 ± 36.7 | 176.2 ± 35.4 | 189.8 ± 48.8 | 192.3 ± 43.0 | 199.1 ± 56.9 |
AST (U/L) | 11.3 ± 6.8 | 10.7 ± 4.3 | 11.9 ± 3.4 | 15.2 ± 10.9 | 11.1 ± 3.8 | 13.1 ± 4.0 | 14.3 ± 4.5 | 15.6 ± 6.1 | 19.9 ± 19.8 |
ALT (U/L) | 10.3 ± 5.9 | 9.8 ± 4.3 | 11.2 ± 7.2 | 12.5 ± 10.7 | 11.1 ± 9.0 | 12.4 ± 5.2 | 14.6 ± 7.4 | 16.1 ± 11.0 | 15.7 ± 9.7 |
γ GTP (U/L) | 18.7 ± 9.7 | 18.5 ± 8.6 | 34.2 ± 63.4 | 29.1 ± 34.5 | 28.9 ± 38.8 | 29.4 ± 27.4 | 26.8 ± 19.2 | 27.6 ± 21.7 | 29.7 ± 20.8 |
Total bilirubin (mg/dL) | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.3 ± 0.1 | 0.2 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.2 ± 0.0 | 0.3 ± 0.1 |
Creatinine (mg/dL) | 13.1 ± 1.9 | 13.2 ± 1.9 | 12.7 ± 1.9 | 12.3 ± 2.0 | 12.4 ± 1.9 | 12.3 ± 1.6* | 11.8 ± 1.7** | 11.7 ± 2.1** | 11.5 ± 2.2*** |
Uric acid (mg/dL) | 8.5 ± 1.3 | 8.3 ± 1.0 | 8.4 ± 1.0 | 8.1 ± 1.1 | 8.1 ± 1.8 | 8.3 ± 1.1 | 8.2 ± 1.4 | 8.2 ± 1.6 | 8.0 ± 1.5 |
BUN (mg/dL) | 76.1 ± 10.5 | 74.6 ± 12.2 | 72.2 ± 13.8 | 66.5 ± 12.3** | 69.4 ± 12.1* | 72.2 ± 14.5 | 71.8 ± 13.2 | 67.2 ± 9.7** | 66.7 ± 14.9* |
BUN after dialysis (mg/dL) | 25.8 ± 6.4 | 24.6 ± 5.5 | 22.8 ± 5.5 | 20.8 ± 5.4** | 20.7 ± 5.8** | 20.5 ± 6.8** | 20.6 ± 5.8** | 18.8 ± 4.7*** | 18.5 ± 5.2*** |
TG (mg/dL) | 131.6 ± 70.3 | 145.4 ± 86.4 | 156.4 ± 83.9 | 125.3 ± 72.5 | 134.5 ± 95.6 | 130.6 ± 69.3 | 114.5 ± 49.9 | 128.1 ± 74.7 | 114.3 ± 48.5 |
Total cholesterol (mg/dL) | 175.4 ± 33.6 | 166.4 ± 30.9 | 181.1 ± 39.8 | 170.2 ± 31.8 | 157.5 ± 27.6 | 159.3 ± 46.5 | 182.4 ± 38.1 | 185.3 ± 40.1 | 176.7 ± 38.0 |
HDL-C (mg/dL) | 44.5 ± 15.3 | 43.4 ± 12.6 | 44.3 ± 11.8 | 46.1 ± 13.8 | 52.7 ± 15.3 | 49.3 ± 13.1 | 54.5 ± 11.9 | 49.6 ± 12.4 | 50.0 ± 13.7 |
SBP (mmHg) | 162.4 ± 23.2 | 160.1 ± 21.9 | 157.2 ± 22.8 | 153.3 ± 17.4** | 149.8 ± 16.6* | 149.5 ± 23.6** | 150.9 ± 17.9* | 141.3 ± 22.5** | 144.2 ± 17.6** |
DBP (mmHg) | 92.9 ± 17.4 | 89.1 ± 17.5 | 86.4 ± 17.2** | 86.8 ± 15.3* | 84.9 ± 10.5* | 82.6 ± 15.2*** | 83.5 ± 12.5** | 77.6 ± 12.9** | 79.6 ± 12.6*** |
HR (beats/min) | 78.1 ± 11.2 | 78.4 ± 9.9 | 79.1 ± 10.0 | 75.9 ± 9.6 | 77.1 ± 18.4 | 78.2 ± 12.0 | 74.7 ± 12.3 | 77.0 ± 14.8 | 76.9 ± 10.4 |