Parameter | Before therapy | After therapy | p |
---|---|---|---|
Median [IQR] | Median [IQR] | ||
C-reactive protein (mg/dL) | 15.3 [5.4–30.3] | 8.2 [5.9–13.5] | 0.219 |
Procalcitonin (ng/mL) | 0.96 [0.36–30.34] | 0.89 [0.46–1.49] | 0.156 |
Ferritin (ng/mL) | 605 [549–1302] | 924 [721–1502] | 0.813 |
KL-6 (U/mL) | 554 [329–800] | 350 [249–553] | 0.016 |
PaO2 /FiO2 | 90 [79–153] | 248 [195–274] | 0.016 |
Compliance (mL/cmH2O) | 32 [20–40] | 31 [27–59] | 0.375 |
Creatinine (mg/dL) | 1.14 [0.86–1.35] | 1.00 [0.94–1.43] | 0.688 |
D-dimer (μg/mL) | 11.7 [4.6–21.1] | 8.3 [6.9–8.8] | 0.813 |
Heart rate (beat/min) | 101 [83–107] | 113 [100–119] | 0.156 |
Mean arterial pressure (mmHg) | 82 [69–96] | 57 [47–66] | 0.016 |
Norepinephrine (μg/kg/min) | 0.10 [0.04–0.16] | 0 | 0.058 |
Lactate (mmol/L) | 1.4 [1.1–2.2] | 1.2 [1.1–1.4] | 0.078 |
Sequential organ failure assessment score | 13 [10–14] | 11 [9–12] | 0.169 |