Improved survival on super high-flux albumin-leaking hemodialysis and online hemodiafiltration with high albumin leakage in patients with mild hypoalbuminemia: evidence and a hypothesis

Table 1 Functional classification of dialyzers developed by the Japanese Society for Dialysis Therapy (JSDT) in 2013 [6]

β₂-Microglobulin clearance (mL/min)^b	Sieving coefficient for albumin^a		Type S
β₂-Microglobulin clearance (mL/min)^b	< 0.03	≥ 0.03
≥ 70	Type II-a Super high-flux^c	Type II-b Super high-flux Albumin-leaking^c
< 70	Type I-a Standard flux^c	Type I-b High -flux Albumin-leaking^c

^aIn vitro using bovine saline test solution with a membrane surface area of 1.5 m², a blood flow rate of 200 ± 4 mL/min, and a filtration flow rate of 15 ± 1 mL/min for measurement of the albumin concentration of the filtrate using the bromocresol green method
^bIn vitro using bovine saline test solution with a membrane surface area of 1.5 m², a blood flow rate of 200 ± 4 mL/min, a dialysate flow rate of 500 ± 15 mL/min, and a filtration flow rate of 15 ± 1 mL/min
^cEnglish notation by the JSDT in 2023

ISSN: 2059-1381