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Table 3 Proposed functional classification of dialyzer membranes and classification of hemodialysis (HD) with reference to the European definition

From: Improved survival on super high-flux albumin-leaking hemodialysis and online hemodiafiltration with high albumin leakage in patients with mild hypoalbuminemia: evidence and a hypothesis

Classification of dialyzer membranes

Classification of HD

Sieving coefficient for albumina

β2-Microglobulin clearance (mL/min)b

Low-flux (LF)

LF HD

0

< 10

High-flux (HF)

HF HD

< 0.01

≥ 20 and < 80

Medium cut-off (MCO)

MCO Expanded HD (HDx)

< 0.01

> 80

Protein leaking (PL)

PL HD

≥ 0.01 and < 0.03

> 80

Super high -flux (SHF) albumin -leaking (AL)

SHF AL HD

≥ 0.03 and < 0.1

> 80

High cut-off (HCO)

HCO HD

< 0.2

Undefined

  1. aIn vitro
  2. bFor conventional HD with a blood flow rate of 200–400 mL/min