Table 1 Patient profiles and serum concentration and protein binding ratio of levofloxacin
From: No effect of protein binding ratio of levofloxacin in hemodialysis patients
Non-HD patients (n = 7) | HD patients (n = 6) | p a | |
|---|---|---|---|
Age (years) | 80.9 ± 12.1 | 75.3 ± 15.3 | 0.48 |
Sex (female/male) | 6/1 | 0/6 | – |
Body weight (kg) | 44.5 ± 12.2 | – | – |
Dry weight (kg) | – | 60.6 ± 18.4 | 0.09 |
Serum creatinine (mg/dL) | 0.7 ± 0.3 | 8.9 ± 3.9 | <0.05 |
Total protein (g/dL) | 6.3 ± 0.4 | 6.2 ± 0.7 | 0.63 |
Albumin (g/dL) | 3.1 ± 0.4 | 3.4 ± 0.5 | 0.35 |
Serum concentration of LVFX (mg/L) | 4.5 ± 2.6 | 5.2 ± 2.3 | 0.62 |
Protein binding ratio of LVFX (%) | 31.2 ± 5.3 | 29.3 ± 6.4 | 0.55 |