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Table 1 Patient profiles and serum concentration and protein binding ratio of levofloxacin

From: No effect of protein binding ratio of levofloxacin in hemodialysis patients

  Non-HD patients (n = 7) HD patients (n = 6) p a
Age (years) 80.9 ± 12.1 75.3 ± 15.3 0.48
Sex (female/male) 6/1 0/6
Body weight (kg) 44.5 ± 12.2
Dry weight (kg) 60.6 ± 18.4 0.09
Serum creatinine (mg/dL) 0.7 ± 0.3 8.9 ± 3.9 <0.05
Total protein (g/dL) 6.3 ± 0.4 6.2 ± 0.7 0.63
Albumin (g/dL) 3.1 ± 0.4 3.4 ± 0.5 0.35
Serum concentration of LVFX (mg/L) 4.5 ± 2.6 5.2 ± 2.3 0.62
Protein binding ratio of LVFX (%) 31.2 ± 5.3 29.3 ± 6.4 0.55
  1. Values represent means ± standard deviation
  2. HD hemodialysis, LVFX levofloxacin
  3. aThe statistical difference was determined by Student’s t test for non-HD patients vs. HD patients. Statistical analysis of weight involving total body weight in non-HD patients vs. dry weight in HD patients