Table 1 Reports of recurrent C3 glomerulopathy after renal transplantation

Athanasiou Y et al (2011) [9]

CFHR5 nephropathy

91

18

10

Unknown

One patient had a second transplant. Eight patients are well 1 to 23 years intact (Cr 0.9 mg/dl).

Servais et al (2007) [10]

Glomerulonephritis (GN) with isolated C3 deposits

19

3

2

1

No recurrence at 2 months after transplantation (C3NeF +). Recurrence at 1 month after transplantation with proteinuria and normal renal function (C3NeF −).

Olivia Boyer et al (2008) [11]

Atypical hemolytic and uremic syndrome associated with CFH deficiency

2

2

2

2

C3 deposition was positive at 5 years post-transplantation.

Kidney function is stable 9 years after transplantation.

Recurrence of GN with isolated C3 deposits 5 months later after kidney transplantation and TMA 4 years later. Six years later, kidney function was stable with regular plasma therapy.

Sethi et al (2012) [1]

C3 GN

12

2

2

2

Recurrence of C3 GN within 1 to 1.5 years of kidney transplantation. (One was C3NeF positive, another was C3 risk allele positive.)

Vernon KA et al (2011) [12]

CFHR5 nephropathy

1

1

1

1

Right after the transplantation, persistent microscopic hematuria was observed.