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Fig. 1 | Renal Replacement Therapy

Fig. 1

From: In silico trials using Monte Carlo simulation to evaluate ciprofloxacin and levofloxacin dosing in critically ill patients receiving prolonged intermittent renal replacement therapy

Fig. 1

PTA of ciprofloxacin/levofloxacin regimens at different MICs in virtual patients with Gram-negative infection in PIRRT. Early PIRRT is when the first intravenous ciprofloxacin or levofloxacin dose is administered with the commencement of an 8-h daily PIRRT session. Late PIRRT is when the first intravenous fluoroquinolone dose is administered 16 h before a daily 8-h PIRRT session. The PTA results were the average of PTA on each 24 h period during the initial 72 h therapy in virtual patients with 8-h hemodialysis PIRRT with 5 L/h of dialysate flow rate

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