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Table 1 Baseline demographic and laboratory data in patients dichotomized at the median of serum bilirubin levels

From: Association of serum bilirubin levels with mortality in patients with diabetes initiating chronic hemodialysis: a competing risks analysis of a single-center cohort

  Below the median (n = 191) Above the median (n = 204) p value
Age (years) 59 ± 13 62 ± 12 0.012
Men (%) 73.8 76.5 0.562
Type 2 diabetes (%) 91.1 96.1 0.061
Duration of diabetes (years) 18 ± 9 19 ± 10 0.617
Diabetic retinopathy (%) 92.7 77.5 <0.001
Medication for diabetes (none/oral/insulin) 25.1/6.3/68.6 25.5/17.2/57.3 0.002
BMI (kg/m2) 24.7 ± 4.2 24.9 ± 4.8 0.648
Systolic blood pressure (mmHg) 157 ± 24 151 ± 19 0.007
Diastolic blood pressure (mmHg) 78 ± 13 77 ± 13 0.764
Smoking (current or ever, %) 62.3 58.8 0.537
ASCVD (%) 57.1 44.1 0.012
Date of hemodialysis initiation    
 January 2003–December 2008 77.5 33.3 <0.001
 January 2009–March 2013 22.5 66.7  
Laboratory data
 Hemoglobin (g/dL) 8.8 ± 1.2 9.3 ± 1.2 <0.001
 HbA1c (NGSP) (%) 6.2 ± 1.1 6.3 ± 1.0 0.522
 Triglycerides (mg/dL) 125 (38–1358) 114 (29–887) 0.163
 HDL cholesterol (mg/dL) 42 ± 15 44 ± 14 0.202
 LDL cholesterol (mg/dL) 106 ± 39 96 ± 36 0.009
 Albumin (g/dL) 3.0 ± 0.5 3.2 ± 0.4 <0.001
 Creatinine (mg/dL) 8.58 ± 2.25 8.26 ± 1.89 0.123
 eGFR (mL/min/1.73 m2) 5.7 ± 1.5 6.0 ± 2.5 0.130
 Total bilirubin (mg/dL) 0.2 (0.1–0.2) 0.4 (0.3–0.8) <0.001
 AST (U/L) 17 ± 10 17 ± 8 0.977
 ALT (U/L) 13 ± 12 12 ± 9 0.593
 γ-GT (U/L) 18 (5–235) 17 (7–416) 0.828
  1. Data are expressed as percentage, mean ± SD, or median (range)
  2. BMI body mass index, ASCVD atherosclerotic cardiovascular disease, eGFR estimated glomerular filtration rate, AST aspartate transaminase, ALT alanine transaminase, γ-GT γ-glutamyl transferase