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Table 1 Baseline demographic and laboratory data in patients dichotomized at the median of serum bilirubin levels

From: Association of serum bilirubin levels with mortality in patients with diabetes initiating chronic hemodialysis: a competing risks analysis of a single-center cohort

 

Below the median (n = 191)

Above the median (n = 204)

p value

Age (years)

59 ± 13

62 ± 12

0.012

Men (%)

73.8

76.5

0.562

Type 2 diabetes (%)

91.1

96.1

0.061

Duration of diabetes (years)

18 ± 9

19 ± 10

0.617

Diabetic retinopathy (%)

92.7

77.5

<0.001

Medication for diabetes (none/oral/insulin)

25.1/6.3/68.6

25.5/17.2/57.3

0.002

BMI (kg/m2)

24.7 ± 4.2

24.9 ± 4.8

0.648

Systolic blood pressure (mmHg)

157 ± 24

151 ± 19

0.007

Diastolic blood pressure (mmHg)

78 ± 13

77 ± 13

0.764

Smoking (current or ever, %)

62.3

58.8

0.537

ASCVD (%)

57.1

44.1

0.012

Date of hemodialysis initiation

   

 January 2003–December 2008

77.5

33.3

<0.001

 January 2009–March 2013

22.5

66.7

 

Laboratory data

 Hemoglobin (g/dL)

8.8 ± 1.2

9.3 ± 1.2

<0.001

 HbA1c (NGSP) (%)

6.2 ± 1.1

6.3 ± 1.0

0.522

 Triglycerides (mg/dL)

125 (38–1358)

114 (29–887)

0.163

 HDL cholesterol (mg/dL)

42 ± 15

44 ± 14

0.202

 LDL cholesterol (mg/dL)

106 ± 39

96 ± 36

0.009

 Albumin (g/dL)

3.0 ± 0.5

3.2 ± 0.4

<0.001

 Creatinine (mg/dL)

8.58 ± 2.25

8.26 ± 1.89

0.123

 eGFR (mL/min/1.73 m2)

5.7 ± 1.5

6.0 ± 2.5

0.130

 Total bilirubin (mg/dL)

0.2 (0.1–0.2)

0.4 (0.3–0.8)

<0.001

 AST (U/L)

17 ± 10

17 ± 8

0.977

 ALT (U/L)

13 ± 12

12 ± 9

0.593

 γ-GT (U/L)

18 (5–235)

17 (7–416)

0.828

  1. Data are expressed as percentage, mean ± SD, or median (range)
  2. BMI body mass index, ASCVD atherosclerotic cardiovascular disease, eGFR estimated glomerular filtration rate, AST aspartate transaminase, ALT alanine transaminase, γ-GT γ-glutamyl transferase