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Table 1 Baseline characteristics

From: A new risk scoring system for prediction of long-term mortality in patients on maintenance hemodialysis

 

All

Development dataset

Validation dataset

P value

N

622

312

310

 

Male (%)

376 (60.45)

191 (61.22)

185 (59.68)

0.69

Age (years)

52.9 ± 14.1

51.9 ± 14.3

53.9 ± 14.0

0.07

Older (%)

133 (22.09)

63 (20.19)

70 (22.58)

0.47

Vintage (years)

5.7 ± 6.0

5.6 ± 5.7

5.9 ± 6.3

0.84

3.4 (1.2, 8.0)

3.5 (1.2, 7.8)

3.3 (1.3, 8.3)

BMI (kg/m2)

20.7 ± 2.7

20.6 ± 2.7

20.7 ± 2.8

0.83

Low BMI (%)

290 (46.62)

146 (46.79)

144 (46.45)

0.93

DM (%)

170 (27.33)

78 (25)

92 (29.68)

0.19

History of CVD

72 (11.58)

35 (11.22)

37 (11.94)

0.78

Hypertension

619 (99.52)

310 (99.36)

309 (99.68)

0.57

Pre-HD hypertension

619 (99.52)

310 (99.36)

309 (99.68)

0.57

Antihypertensive drug use

378 (60.77)

196 (62.82)

182 (58.71)

0.29

Hypotension during HD

218 (35.05)

105 (33.65)

113 (36.45)

0.46

CTR (%)

50.7 ± 5.0

50.2 ± 5.1

51.2 ± 5.0

0.02

High CTR (%)

330 (53.05)

155 (49.68)

175 (56.45)

0.09

Hemoglobin level (g/dL)

9.5 ± 1.1

9.4 ± 1.0

9.6 ± 1.2

0.07

Controlled hemoglobin level (%)

189 (30.39)

87 (27.88)

102 (32.9)

0.17

Plasma ANP level (pg/mL)

182.4 ± 153.2

180.0 ± 170.8

184.8 ± 133.5

0.10

143 (87.4, 238)

132.5 (79.9, 230.0)

149.5 (91.6, 241.0)

High ANP level (%)

472 (75.88)

231 (74.04)

241 (77.74)

0.28

Plasma BNP level (pg/mL)

474.4 ± 613.4

470.2 ± 699.3

478.6 ± 513.7

0.04

291.5 (150, 587)

261.5 (131.0, 508.0)

335.0 (166.0, 614.0)

High BNP level (%)

477 (76.69)

227 (72.76)

250 (80.65)

0.02

ST segment depression or negative T wave (%)

221 (35.53)

108 (34.62)

113 (36.45)

0.63

Abnormal Q wave (%)

39 (6.27)

20 (6.41)

19 (6.13)

0.89

Atrial fibrillation (%)

14 (2.25)

4 (1.28)

10 (3.23)

0.10

ECG score (%)

   

0.59

 0

380 (61.09)

195 (62.5)

185 (59.68)

 

 1

211 (33.92)

103 (33.01)

108 (34.84)

 2

30 (4.82)

13 (4.17)

17 (5.48)

 3

1 (0.16)

1 (0.32)

0 (0)

All-cause death within 15 years (%)

409 (65.76)

200 (64.1)

209 (73.87)

0.01

All-cause death within 10 years (%)

342 (54.98)

155 (49.68)

187 (60.32)

0.01

All-cause death within 5 years (%)

197 (31.67)

96 (30.77)

101 (32.58)

0.63

CVD-caused death within 15 years (%)

230 (36.98)

102 (32.69)

128 (55.65)

0.03

CVD-caused death within 10 years (%)

197 (31.67)

86 (27.56)

111 (35.81)

0.03

CVD-caused death within 5 years (%)

117 (18.81)

56 (17.95)

59 (19.03)

0.73

Follow-up period (days)

2963.4 ± 1839.3

3043.7 ± 1904.8

2882.5 ± 1770.5

0.28

2813 (1301, 5040)

2908 (1246, 5182)

2712 (1319, 4584)

  1. Variables are expressed as mean ± standard deviation. Vintage, plasma ANP and BNP levels, and follow-up days are also shown as median and interquartile range. Intergroup comparisons of parameters were performed using chi-square test, t test, and Mann Whitney U test as appropriate as appropriate
  2. Development dataset dataset for the development of risk score, Validation dataset dataset for the validation of risk score, Older 65 ≤ age, BMI body mass index, Low BMI BMI <20.4 kg/m2, DM diabetes mellitus as a cause of end-stage renal disease, CVD cardiovascular disease, HD hemodialysis, CTR cardiothoracic ratio, High CTR 50 % ≤ CTR, ANP atrial natriuretic peptide, High ANP level 132.5 pg/mL ≤ plasma ANP level, BNP brain natriuretic peptide, High BNP level 250 pg/mL ≤ plasma BNP level, ECG score the number of abnormal findings in electrocardiogram