|
Parameter
|
Baseline
|
Week 4
|
Week 12
|
Week 26
|
Week 52
|
|---|
|
Number of participants
|
20
|
20
|
19
|
19
|
19
|
|
BUN (mmol/L)
|
25.1 ± 5.2
|
24.3 ± 5.4
|
20.8 ± 6.9*
|
20.8 ± 4.9*
|
23.5 ± 5.2
|
|
Creatinine (μmol/L)
|
1105.4 ± 244.4
|
1079.2 ± 210.6
|
1003.8 ± 286.9
|
1030.2 ± 281.2*
|
1018.7 ± 251.8*
|
|
Total protein (g/L)
|
63.2 ± 5.0
|
64.7 ± 5.4
|
61.3 ± 4.9
|
62.4 ± 7.0
|
63.2 ± 5.4
|
|
Albumin (g/L)
|
37.6 ± 3.1
|
37.3 ± 4.6
|
35.8 ± 4.6
|
36.7 ± 5.3
|
36.1 ± 3.9
|
|
AST (IU/L)
|
12.6 ± 7.3
|
11.4 ± 5.2
|
10.5 ± 4.4
|
12.1 ± 5.9
|
11.5 ± 5.3
|
|
ALT (IU/L)
|
10.8 ± 6.3
|
9.8 ± 4.0
|
9.2 ± 3.5
|
10.5 ± 3.0
|
9.7 ± 5.6
|
|
ALP (IU/L)
|
243.8 ± 94.8
|
218.9 ± 69.7
|
213.6 ± 92.4
|
243.1 ± 133.3
|
224.9 ± 78.7
|
|
Total bilirubin (μmol/L)
|
4.4 ± 1.5
|
4.5 ± 1.7
|
4.4 ± 1.8
|
4.8 ± 2.3
|
4.5 ± 1.3
|
|
LDH (IU/L)
|
186.6 ± 25.5
|
185.0 ± 29.1
|
184.1 ± 31.9
|
191.8 ± 40.0
|
181.7 ± 27.1
|
|
Total cholesterol (mmol/L)
|
4.273 ± 0.710
|
4.439 ± 0.900
|
4.266 ± 0.797
|
4.539 ± 0.918
|
4.241 ± 1.159
|
|
Triglycerides (mmol/L)
|
1.214 ± 0.414
|
1.096 ± 0.281
|
1.036 ± 0.333
|
1.149 ± 0.386
|
1.213 ± 0.635
|
|
HDL cholesterol (mmol/L)
|
1.24 ± 0.39
|
1.38 ± 0.49
|
1.41 ± 0.52
|
1.52 ± 0.72
|
1.30 ± 0.44
|
|
LDL cholesterol (mmol/L)
|
2.41 ± 0.41
|
2.56 ± 0.66
|
2.45 ± 0.63
|
2.53 ± 0.74
|
2.44 ± 0.89
|
-
BUN blood urea nitrogen, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, LDH lactate dehydrogenase
- *p < 0.05 (paired t test vs. baseline, after Bonferroni corrections). Mean ± SD
