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Table 1 Baseline characteristics of the patients

From: Effect of oral and intravenous iron therapy on hemoglobin levels in hemodialysis patients according to serum ferritin level

  IV iron Sodium ferrous citrate Ferric citrate hydrate IV iron Sodium ferrous citrate Ferric citrate hydrate IV iron Sodium ferrous citrate Ferric citrate hydrate
All All All Serum ferritin Serum ferritin Serum ferritin Serum ferritin Serum ferritin Serum ferritin
<100 ng/ml <100 ng/ml <100 ng/ml 100~199 ng/ml 100~199 ng/ml 100~199 ng/ml
N 40 31 16 30 25 12 10 6 4
Female (%) 15 (37.5) 3 (9.7)a 6 (37.5)b 12 (40.0) 3 (25.0)a 5 (41.7) 3 (30.0) 0 (0.0) 1 (25.0)
Age (years) 70.9 ± 9.2 73.3 ± 9.6a 65.5 ± 10.9b 69.3 ± 8.5 65.8 ± 12.1a 76.0 ± 5.0c 75.6 ± 10.2 64.3 ± 3.7a 65.3 ± 15.8
Duration on dialysis (months) 87.5 ± 104.7 43.5 ± 58.3a 80.1 ± 107.2 92.2 ± 101.4 39.2 ± 51.6a 80.5 ± 120.3 73.4 ± 118.6 61.3 ± 84.7 79.0 ± 66.0
Diabetes (%) 15 (37.5) 17 (54.8) 8 (50.0) 10 (33.3) 14 (56.0) 6 (50.0) 5 (50.0) 3 (50.0) 2 (50.0)
Hemoglobin (g/dl) 9.8 ± 0.9 9.6 ± 1.2 10.0 ± 1.2 9.7 ± 0.9 9.8 ± 1.2 9.8 ± 1.1 10.0 ± 0.5 8.9 ± 1.1a 10.8 ± 1.5b
ESAs (μg/4 weeks) 104.6 ± 44.0 116.0 ± 44.6 101.9 ± 43.1 109.3 ± 45.5 120.6 ± 46.3 112.5 ± 43.3 90.5 ± 37.5 96.7 ± 32.7 70.0 ± 24.5
C.E.R.A. (N) 34 24 15 27 21 11 7 3 4
Darbepoetin alfa (N) 6 7 1 3 4 1 3 3 0
CRP (mg/dl) 0.18 ± 0.24 0.27 ± 0.45 0.31 ± 0.63 0.18 ± 0.26 0.20 ± 0.35 0.19 ± 0.31 0.17 ± 0.16 0.57 ± 0.69 0.68 ± 1.17
Serum alb (g/dl) 3.5 ± 0.3 3.6 ± 0.3 3.7 ± 0.2 3.6 ± 0.3 3.6 ± 0.3 3.6 ± 0.2 3.5 ± 0.2 3.6 ± 0.5 3.8 ± 0.3
p (mg/dl) 4.8 ± 1.0 5.0 ± 1.1 5.6 ± 1.3a 4.9 ± 1.1 5.1 ± 1.1 5.4 ± 1.2 4.6 ± 0.8 4.7 ± 0.7 6.3 ± 1.3a, b
Intact PTH (pg/ml) 173.6 ± 95.1 179.4 ± 115.3 160.8 ± 148.8 171.2 ± 103.5 156.1 ± 77.3 172.8 ± 168.1 180.8 ± 67.6 276.3 ± 192.4 124.5 ± 68.8
Ferritin (ng/ml) 79.4 ± 45.3 65.1 ± 35.7 74.4 ± 43.8 57.8 ± 25.2 51.3 ± 22.2 52.8 ± 20.4 144.4 ± 24.0 122.4 ± 19.9 139.1 ± 25.3
Fe (μg/dl) N.A. 76.5 ± 23.4 73.3 ± 31.6 N.A. 80.4 ± 22.3 75.6 ± 33.0 N.A. 60.2 ± 22.5 66.8 ± 31.1
  1. N.A. not available
  2. aThe difference is statistically significant versus IV iron group (p < 0.05)
  3. bThe difference is statistically significant versus sodium ferrous citrate group (p < 0.05)
  4. cThe difference is statistically significant versus sodium ferrous citrate group (p < 0.001)