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Table 5 Characteristics of patient-created AVF with and without early VA failure

From: Factors associated with early failure of vascular access in acute-phase patients

Parameter

Without failure (n = 296)

With failure (n = 35)

P value

Age (years)

66.4 ± 15.0

67.8 ± 17.1

0.5903

Male (%)

68.2

57.1

0.1864

Diabetes (%)

45.6

48.6

0.7393

Hypertension (%)

70.6

71.4

0.9197

Atrial fibrillation (%)

8.5

11.4

0.5551

Primary cause of admission

 Exacerbation of CRF (%)

65.9

62.9

0.7221

 Heart disease (%)

13.9

14.3

0.9440

 Heart failure (%)

10.5

14.3

0.4933

 Coronary artery disease (%)

2.0

0.0

0.3953

 Infectious disease (%)

5.4

8.6

0.4464

 Malignancy (%)

4.1

5.7

0.6444

 Cephalopathy (%)

3.0

2.9

0.9522

 Cerebral infarction (%)

0.7

2.9

0.1978

 Intracranial hemorrhage (%)

1.0

0.0

0.5496

 Peripheral artery disease (%)

0.7

2.9

0.1978

 Aortic disease (%)

1.4

0.0

0.4890

 Others (%)

5.7

2.9

0.4764

Warfarin (%)

10.5

11.4

0.8620

Antiplatelet agent (%)

27.0

22.9

0.5975

Statin (%)

32.4

22.9

0.2485

ACEi or ARB (%)

49.0

45.7

0.7142

Beta blocker (%)

33.1

25.7

0.3765

CCB (%)

63.5

71.4

0.3552

LVEF (%)

56.0 ± 12.5

56.8 ± 13.3

0.7316

SBP (mmHg)

138.9 ± 24.7

132.6 ± 23.4

0.1568

DBP (mmHg)

75.5 ± 16.6

71.1 ± 14.5

0.1309

WBC (103/μL)

7.2 ± 3.2

8.4 ± 3.6

0.0376*

Hb (g/dL)

9.7 ± 1.8

9.7 ± 1.7

0.8780

PLT (104/μL)

19.2 ± 8.1

21.2 ± 8.9

0.1666

TP (g/dL)

6.1 ± 0.9

5.8 ± 0.9

0.0540

ALB (g/dL)

3.1 ± 0.6

2.6 ± 0.7

0.0006**

BUN (mg/dL)

70.1 ± 29.2

60.2 ± 27.8

0.0578

Cr (mg/dL)

7.6 ± 3.0

6.9 ± 2.6

0.1933

eGFR (mL/min/1.7 m2)

7.1 ± 3.8

7.4 ± 3.5

0.6445

AST (IU/L)

22.6 ± 20.3

21.9 ± 12.0

0.8438

ALT (IU/L)

18.6 ± 20.9

15.6 ± 15.9

0.4238

CRP (mg/dL)

2.3 ± 3.4

2.7 ± 4.6

0.5259

APTT

30.7 ± 14.2

28.7 ± 4.7

0.4961

PT-INR

1.17 ± 0.42

1.14 ± 0.25

0.6554

  1. VA vascular access, CRF chronic renal failure, ACEi angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker, LVEF left ventricular ejection fraction, SBP systolic blood pressure, DBP diastolic blood pressure, WBC white blood cell, Hb hemoglobin, PLT platelet, TP total protein, ALB albumin, BUN blood urea nitrogen, Cr creatinine, eGFR estimated glomerular filtration rate, AST aspartate aminotransferase, ALT Alanine transaminase, CRP C-reactive protein, APTT activated partial thromboplastin time, PT-INR international normalized ratio of prothrombin time
  2. *P < 0.05; **P < 0.01