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Table 1 Patient characteristics and results of univariate logistic regression analysis of association between AR

From: Risk factors for allergic reaction at initial therapeutic plasma exchange in a single-center study: beware of high rates of severe allergic reaction

  Whole cohort (n = 88) P value
Age (years) 57 (36–70) 0.01**
Gender, men 52 (59%) 0.71
Body weight (kg) 54 (48–63) 0.12*
Use of steroid before TPE 72 (77%)  
Start of steroid use No steroid on day of TPE Reference
 The day of TPE 5 (6%) 0.15*
 1–7 days before TPE 24 (27%) 0.29
 >7 days before TPE 39 (44%) 0.40
Prednisolone-equivalent dose on day of TPE (mg/day) 20 (0.63–60) 0.63
Use of immunosuppressant before TPE 26 (28%) 0.04**
History of allergy 26 (30%) 0.47
History of blood transfusion 27 (31%) 0.07*
Indication for TPE   
 ABO-incompatible kidney transplantation 13 (15%) Reference
 Hepatic failure 18 (20%) 0.01**
 Others 57 (65%) 0.11*
Amount of FFP (units/kg) 0.69 (0.60–0.75) 0.14*
White blood cell count (/μl) 8850 (5100–13,100) 0.04**
Hemoglobin (g/dl) 8.8 (7.0–10.7) 0.80
Platelet count (103/μl) 108 (54.5–217.8) 0.59
Serum creatinine (mg/dl) 2.77 (0.69–6.25) 0.02**
Serum albumin (g/dl) 3.0 (2.6–3.5) 0.33
Serum C-reactive protein (mg/dl) 1.12 (0.16–4.52) 0.39
  1. Data presented as median (interquartile range) or n (%)
  2. FFP fresh frozen plasma, TPE therapeutic plasma exchange
  3. *P < 0.2, ** < 0.05 the correlation in univariate logistic regression analysis. Categories that were associated in P < 0.2 were adapted to multivariate analysis