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Table 1 Patient characteristics and results of univariate logistic regression analysis of association between AR

From: Risk factors for allergic reaction at initial therapeutic plasma exchange in a single-center study: beware of high rates of severe allergic reaction

 

Whole cohort (n = 88)

P value

Age (years)

57 (36–70)

0.01**

Gender, men

52 (59%)

0.71

Body weight (kg)

54 (48–63)

0.12*

Use of steroid before TPE

72 (77%)

 

Start of steroid use

No steroid on day of TPE

Reference

 The day of TPE

5 (6%)

0.15*

 1–7 days before TPE

24 (27%)

0.29

 >7 days before TPE

39 (44%)

0.40

Prednisolone-equivalent dose on day of TPE (mg/day)

20 (0.63–60)

0.63

Use of immunosuppressant before TPE

26 (28%)

0.04**

History of allergy

26 (30%)

0.47

History of blood transfusion

27 (31%)

0.07*

Indication for TPE

  

 ABO-incompatible kidney transplantation

13 (15%)

Reference

 Hepatic failure

18 (20%)

0.01**

 Others

57 (65%)

0.11*

Amount of FFP (units/kg)

0.69 (0.60–0.75)

0.14*

White blood cell count (/μl)

8850 (5100–13,100)

0.04**

Hemoglobin (g/dl)

8.8 (7.0–10.7)

0.80

Platelet count (103/μl)

108 (54.5–217.8)

0.59

Serum creatinine (mg/dl)

2.77 (0.69–6.25)

0.02**

Serum albumin (g/dl)

3.0 (2.6–3.5)

0.33

Serum C-reactive protein (mg/dl)

1.12 (0.16–4.52)

0.39

  1. Data presented as median (interquartile range) or n (%)
  2. FFP fresh frozen plasma, TPE therapeutic plasma exchange
  3. *P < 0.2, ** < 0.05 the correlation in univariate logistic regression analysis. Categories that were associated in P < 0.2 were adapted to multivariate analysis