Table 1 Effects of aldosterone in associated disorders [25]

Effects of aldosterone

Myocardial fibrosis and remodeling

Vascular injury and fibrosis

Reduced vascular compliance

Impaired baroreceptor function

Endothelial dysfunction

Catecholamine potentiation

Ventricular arrhythmias

Progressive renal disease

K⁺ and Mg²⁺ loss

Sodium reabsorption and water retention

Prothrombotic effects (Increasing PAI-1)

Aldosterone-associated disorders

Hypertension

Heart failure and cardiac hypertrophy

Stroke

Ischemia and arteriosclerosis

End-stage renal disease

Peritoneal fibrosis