Unadjusted | Model 1 | Model 2 | ||||
---|---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | |
All-cause mortality | ||||||
Q1 | 1 (Reference) | <0.001† | 1 (Reference) | <0.001† | 1 (Reference) | 0.003† |
Q2 | 1.23 (0.52 to 2.93) | 0.95 (0.37 to 2.49) | 0.71 (0.26 to 1.96) | |||
Q3 | 3.06 (1.43 to 6.52) | 2.24 (0.98 to 5.16) | 1.94 (0.83 to 4.58) | |||
Q4 | 4.37 (2.10 to 9.10) | 4.37 (1.94 to 9.84) | 3.12 (1.26 to 7.74) | |||
per 104 cells/μL | 1.29 (1.18 to 1.42) | <0.001 | 1.37 (1.23 to 1.53) | <0.001 | 1.33 (1.17 to 1.51) | <0.001 |
Cardiovascular mortality | ||||||
Q1 | 1 (Reference) | <0.001† | 1 (Reference) | 0.005† | 1 (Reference) | 0.03† |
Q2 | 1.86 (0.56 to 6.19) | 1.91 (0.47 to 7.62) | 1.59 (0.37 to 6.79) | |||
Q3 | 5.59 (1.92 to 16.27) | 4.97 (1.41 to 17.46) | 4.18 (1.14 to 15.25) | |||
Q4 | 5.67 (1.94 to 16.59) | 6.57 (1.85 to 23.34) | 4.93 (1.24 to 19.56) | |||
per 104 cells/μL | 1.28 (1.14 to 1.43) | <0.001 | 1.37 (1.19 to 1.56) | <0.001 | 1.38 (1.17 to 1.63) | <0.001 |