Table 2 Pathological features and Banff score
Feature | Banff term | Banff Score | |||
|---|---|---|---|---|---|
0 | 1 | 2 | 3 | ||
Interstitial inflammation (% of nonfibrotic cortex) | i | <10% | 10–25% | 26–50% | >50% |
Total inflammation (% all cortex) | ti | <10% | 10–25% | 26–50% | >50% |
Tubulitis (maximum mononuclear cells/tubule) | t | 0 | 1–4 | 5–10 | >10 |
Arterial inflammation (% lumen endarteritis) | V | None | <25% | >25% | Transmural or necrosis |
Glomerulitis (% glomeruli involved) | g | None | <25% | 26–50% | >50% |
Capillaritis (cells per cortical PTC, requires >10% of PTC to be affected for scoring) | ptc | <10% | <5/PTC | 5–10/PTC | >10/PTC |
C4d deposition in PTC (% positive) | C4d | 0% | l–9% | 10–50% | >50% |
Interstitial fibrosis (% of cortex) | ci | <5% | 6–25% | 26–50% | >50% |
Tubular atrophy (% cortex) | ct | 0% | <25% | 26–50% | >50% |
Arterial intimal thickening (% narrowing lumen of most severely affected glomerulus) | cv | 0% | <25% | 26–50% | >50% |
Transplant glomerulopathy (% of capillaries with duplication in most severely affected glomerulus) | cg | 0% | <25% | 26–50% | >50% |
Arteriolar hyalinosis (number with focal or circumferential hyaline) | ah | None | 1 focal | >1 focal | 1 circumferential >50% |
Mesangial matrix increase (% affected glomeruli) | mm | 0% | <25% | 26–50% | >50% |