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Table 1 Patient baseline clinical characteristics

From: Virological response to daclatasvir and asunaprevir combination therapy for chronic hepatitis C virus genotype 1b infection in dialysis patients: a prospective, multicenter study

Characteristics

 

All patients

N

 

30

Age, years

 

65.5 ± 7.7

Sex, male

n (%)

23 (76.7)

Duration of hemodialysis

years

15.4 ± 10.5

Etiology of end-stage renal disease

n (%)

 

 Diabetic nephropathy

 

13 (43.3)

 Polycystic kidney disease

 

2 (6.7)

 Interstitial nephritis

 

3 (10.0)

 Glomerulonephritis

 

7 (23.3)

 Others

 

5 (16.7)

Weight

kg

51.2 ± 10.1

Previous treatment

n (%)

 

 Naïve

 

21 (70.0)

 Relapse

 

5 (16.6)

 Non-viral response

 

4 (13.3)

Liver cirrhosis

n (%)

9 (30.0)

Serum HCV-RNA levels

log10IU/mL

5.15 ± 0.95

NS5A inhibitor RAVs

n (%)

2 (6.7)

Laboratory data

 Hemoglobin

g/dL

10.6 ± 1.50

 WBC

/μL

5484 ± 1760

 Neutrophils

/μL

3718 ± 1381

 Platelets

×104/μL

16.5 ± 6.38

 Serum AST

IU/L

20.1 ± 13.1

 Serum ALT

IU/L

16.1 ± 8.21

 Serum albumin

g/dL

3.40 ± 0.35

 BUN

mg/dL

51.9 ± 16.5

 Serum creatinine

mg/dL

9.31 ± 2.39

 Serum total bilirubin

mg/dL

0.36 ± 0.16

 Alpha-fetoprotein

ng/mL

2.39 ± 0.98

  1. Data are expressed as median, number (%), or mean ± standard deviation
  2. RAVs resistance-associated variants, BUN blood urea nitrogen, PT-INR international normalized ratio of prothrombin time