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Table 2 Effect on renal anemia during study period and changes in nutritional status and CRP

From: Efficacy of Saxagliptin versus Mitiglinid in patients with type 2 diabetes and end-stage renal disease

 

Saxagliptin

 

Mitiglinide

 

Pre

Post

P value

Pre

Post

P value

Hb (g/dL)

10.5 ± 0.8

10.9 ± 0.8

0.1523

10.7 ± 0.9

10.7 ± 0.7

0.9855

DA (μg/w)

22.0 ± 22.6

16.8 ± 22.1

0.2238

15.5 ± 10.7

19.5 ± 11.5

0.1343

Fe (mg/dL)

58.1 ± 21.0

73.9 ± 25.0

0.0085

70.8 ± 34.2

68.5 ± 25.9

0.733

TIBC (mg/dL)

295.8 ± 58.5

296.6 ± 62.1

0.921

285.4 ± 34.7

286.7 ± 50.5

0.8657

TSAT (%)

20.2 ± 7.7

25.9 ± 10.5

0.0148

25.3 ± 12.8

24.5 ± 9.5

0.7349

Ferritin (ng/mL)

58.8 ± 145.0

40.3 ± 37.7

0.5738

33.5 ± 29.7

54.1 ± 99.2

0.3343

DW (kg)

62.4 ± 9.6

62.1 ± 9.9

0.3695

67.7 ± 18.4

68.0 ± 18.6

0.7227

ERI

6.9 ± 7.0

5.6 ± 8.3

0.3769

5.0 ± 4.1

5.8 ± 3.8

0.3522

Alb (g/dL)

3.7 ± 0.3

3.8 ± 0.3

0.2698

3.7 ± 0.3

3.7 ± 0.2

0.5929

TC (mg/dL)

148.9 ± 38.2

148.2 ± 39.7

0.852

148.4 ± 41.2

147.4 ± 41.9

0.8656

HDL-C (mg/dL)

43.4 ± 10.9

46.0 ± 11.2

0.1802

38.8 ± 12.0

39.3 ± 12.7

0.6884

LDL-C (mg/dL)

83.6 ± 26.7

83.1 ± 27.8

0.8805

76.9 ± 24.4

81.8 ± 33.3

0.276

TG (mg/dL)

126.0 ± 85.0

126.6 ± 89.6

0.9351

187.6 ± 178.4

163.2 ± 123.1

0.2044

CRP (mg/dL)

0.16 ± 0.17

0.17 ± 0.18

0.6847

0.20 ± 0.26

0.33 ± 0.31

0.1201

  1. Hb hemoglobin, DA darbepoetin alfa, TIBC total iron binding capacity, TSAT transferrin saturation, DW dry weight, ERI erythropoietin responsiveness index, Alb albumin, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride, CRP C-reactive protein