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Table 2 Effect on renal anemia during study period and changes in nutritional status and CRP

From: Efficacy of Saxagliptin versus Mitiglinid in patients with type 2 diabetes and end-stage renal disease

  Saxagliptin   Mitiglinide  
Pre Post P value Pre Post P value
Hb (g/dL) 10.5 ± 0.8 10.9 ± 0.8 0.1523 10.7 ± 0.9 10.7 ± 0.7 0.9855
DA (μg/w) 22.0 ± 22.6 16.8 ± 22.1 0.2238 15.5 ± 10.7 19.5 ± 11.5 0.1343
Fe (mg/dL) 58.1 ± 21.0 73.9 ± 25.0 0.0085 70.8 ± 34.2 68.5 ± 25.9 0.733
TIBC (mg/dL) 295.8 ± 58.5 296.6 ± 62.1 0.921 285.4 ± 34.7 286.7 ± 50.5 0.8657
TSAT (%) 20.2 ± 7.7 25.9 ± 10.5 0.0148 25.3 ± 12.8 24.5 ± 9.5 0.7349
Ferritin (ng/mL) 58.8 ± 145.0 40.3 ± 37.7 0.5738 33.5 ± 29.7 54.1 ± 99.2 0.3343
DW (kg) 62.4 ± 9.6 62.1 ± 9.9 0.3695 67.7 ± 18.4 68.0 ± 18.6 0.7227
ERI 6.9 ± 7.0 5.6 ± 8.3 0.3769 5.0 ± 4.1 5.8 ± 3.8 0.3522
Alb (g/dL) 3.7 ± 0.3 3.8 ± 0.3 0.2698 3.7 ± 0.3 3.7 ± 0.2 0.5929
TC (mg/dL) 148.9 ± 38.2 148.2 ± 39.7 0.852 148.4 ± 41.2 147.4 ± 41.9 0.8656
HDL-C (mg/dL) 43.4 ± 10.9 46.0 ± 11.2 0.1802 38.8 ± 12.0 39.3 ± 12.7 0.6884
LDL-C (mg/dL) 83.6 ± 26.7 83.1 ± 27.8 0.8805 76.9 ± 24.4 81.8 ± 33.3 0.276
TG (mg/dL) 126.0 ± 85.0 126.6 ± 89.6 0.9351 187.6 ± 178.4 163.2 ± 123.1 0.2044
CRP (mg/dL) 0.16 ± 0.17 0.17 ± 0.18 0.6847 0.20 ± 0.26 0.33 ± 0.31 0.1201
  1. Hb hemoglobin, DA darbepoetin alfa, TIBC total iron binding capacity, TSAT transferrin saturation, DW dry weight, ERI erythropoietin responsiveness index, Alb albumin, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride, CRP C-reactive protein