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Table 1 Comparison of characteristics and infection biomarkers between the localized infection group and the no infection group

From: Presepsin is a potent biomarker for diagnosing skin wound infection in hemodialysis patients compared to white blood cell count, high-sensitivity C-reactive protein, procalcitonin, and soluble CD14

  All patients Patients examined for all biomarkers including sCD14 and PCT
Group Localized infection No infection Localized infection No infection
Number 29 20 12 8
Age, years 72 (66–77) 78 (74–83) 73 (65–78) 78 (72–84)
Male, % 48.3 55.0 66.7 62.5
WBC, μL 5700 (4333–7100) 5250 (4475–6000) 5800 (4675–6735) 5450 (4475–5750)
hsCRP, mg/dL 1.26 (0.71–2.24)* 0.23 (0.10–1.22) 1.30 (0.50–2.16) 0.17 (0.11–0.74)
Presepsin, pg/mL 3370 (2240–4480)** 1510 (1205–1810) 3330 (2515–3990)* 1560 (1488–1973)
sCD14, ng/mL    2278 (1969–2906) 2417 (2226–2732)
PCT, ng/mL    0.23 (0.20–0.27) 0.25 (0.21–0.28)
  1. Data were presented as the median (interquartile range, IQR). Statistics were analyzed using the Mann-Whitney U test. A blood analysis was performed to determine the WBC count, and the hsCRP and presepsin levels of 49 HD patients who were enrolled in 2014/1/1–2015/3/31 (shown as “all patients”). sCD14 and PCT were also measured in the 20 HD patients enrolled after 2015/1/1 (shown as “patients examined for all biomarkers including sCD14 and PCT”)
  2. *P < 0.05, **P < 0.01 vs. the no infection group