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Table 4 Clinical trials of erythropoiesis-stimulating agents in predialysis chronic kidney disease patients

From: 2015 Japanese Society for Dialysis Therapy: Guidelines for Renal Anemia in Chronic Kidney Disease

  Number %DM High Hb level group Low Hb level group
Baseline Target Achieved Baseline Target Achieved
A21 2012 322 31 9.2 11–13 12 9.2 9–11 9.8
TREAT 2009 4038 100 10.5 13 12.5 10.4 >9 (rescue) 10.6
ACORD 2007 172 100 11.9 13–15 13.5 11.9 10.5–11.5 12.1
CREATE 2006 603 26 11.6 13–15 13.3 11.6 10.5–11.5 11.8
CHOIR 2006 1432 49 10.1 13.5 12.6 10.1 11.5 11.3
Gouva 2004 88 0 10.1 >13 12.9 10.1 >9 10.3
Kuriyama 1997 108   9.3 Treated 11.8 9 Untreated 8.3