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Table 2 Summary of adverse events with FCH treatment

From: Long-term iron accumulation in dialysis patients treated with ferric citrate hydrate: a single-center, 80-week retrospective study in Japan

Adverse events

Total

N = 136 (%)

HD

n = 104 (%)

VS.

PD

n = 32 (%)

Any adverse event

59

(43.4)

47

(45.2)

 

12

(37.5)

 Hemoglobin overshoot, >13 g/dL

12

(8.8)

11

(10.6)

 

1

(3.1)

 Ferritin overload, >300 ng/dL

5

(3.6)

0

(0)

 

5

(15.6)

 Gastrointestinal symptoms

17

(12.5)a

17

(16.3)

 

0

(0)

 Hypophosphatemia, <3.5 mg/dL

5

(3.7)

3

(2.9)

 

2

(6.3)

 Death

10

(7.4)

7

(6.7)

 

3

(9.4)

 Other

10

(7.4)b

9

(8.7)

 

1

(3.1)

  1. HD hemodialysis, PD peritoneal dialysis
  2. aAny digestive trouble; nine diarrhea, four constipation, four abdominal discomfort
  3. bOther; four nothing by mounth, four darkening of stools, one itching, one eosinophilia