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Table 3 Multiple regression analysis for risk factors for increase in serum ferritin levels at 40 weeks

From: Long-term iron accumulation in dialysis patients treated with ferric citrate hydrate: a single-center, 80-week retrospective study in Japan

Variables

Regression coefficient

95% CI

P value

Method of dialysis (PD)

105.91

(66.64 to 145.19)

<0.001***

Diabetes mellitus (1)

10.56

(−23.65 to 44.77)

0.539

Body mass index (per 1%)

−5.00

(−8.63 to −1.36)

0.008**

Phosphorus (per 1 mg/dL)

2.27

(−13.08 to 17.63)

0.768

Mean FCH dose (per 1 mg/day)

−2.80

(−13.25 to 7.65)

0.594

Hemoglobin (per 1 g/dL)

14.18

(−10.81 to 39.17)

0.261

Reticulocyte count (per 1‰)

5.02

(1.93 to 8.12)

0.002**

Erythropoiesis resistance index (per 1)

2.55

(0.00 to 5.10)

0.050*

Transferrin saturation (per 1%)

−1.63

(−3.73 to 0.48)

0.127

Ferritin (per 1 ng/mL)

−0.10

(−0.62 to 0.41)

0.687

Albumin (per 1 g/dL)

42.56

(−10.06 to 95.18)

0.111

C-reactive protein (per 1 mg/dL)

−35.00

(−84.85 to 14.86)

0.165

β2-microglobulin (per 1 mg/L)

−1.42

(−4.66 to 1.81)

0.382

  1. CI confidence interval, PD peritoneal dialysis, FCH ferric citrate hydrate
  2. *P < 0.05, **P < 0.01, ***P < 0.001