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Table 3 Multiple regression analysis for risk factors for increase in serum ferritin levels at 40 weeks

From: Long-term iron accumulation in dialysis patients treated with ferric citrate hydrate: a single-center, 80-week retrospective study in Japan

Variables Regression coefficient 95% CI P value
Method of dialysis (PD) 105.91 (66.64 to 145.19) <0.001***
Diabetes mellitus (1) 10.56 (−23.65 to 44.77) 0.539
Body mass index (per 1%) −5.00 (−8.63 to −1.36) 0.008**
Phosphorus (per 1 mg/dL) 2.27 (−13.08 to 17.63) 0.768
Mean FCH dose (per 1 mg/day) −2.80 (−13.25 to 7.65) 0.594
Hemoglobin (per 1 g/dL) 14.18 (−10.81 to 39.17) 0.261
Reticulocyte count (per 1‰) 5.02 (1.93 to 8.12) 0.002**
Erythropoiesis resistance index (per 1) 2.55 (0.00 to 5.10) 0.050*
Transferrin saturation (per 1%) −1.63 (−3.73 to 0.48) 0.127
Ferritin (per 1 ng/mL) −0.10 (−0.62 to 0.41) 0.687
Albumin (per 1 g/dL) 42.56 (−10.06 to 95.18) 0.111
C-reactive protein (per 1 mg/dL) −35.00 (−84.85 to 14.86) 0.165
β2-microglobulin (per 1 mg/L) −1.42 (−4.66 to 1.81) 0.382
  1. CI confidence interval, PD peritoneal dialysis, FCH ferric citrate hydrate
  2. *P < 0.05, **P < 0.01, ***P < 0.001