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Table 2 Effect of prescription doses of phosphate binders and ESA after 5 months of observation

From: Comparative analysis of the phosphate-binding effects of sucroferric oxyhydroxide, ferric citrate, and lanthanum carbonate

  

Mean

SD

SE

ANOVA

95% CI

Minimum

Maximum

      

Lower limit

Upper limit

  

Total amount of prescription dose (per 5 months)

FC

142.9

80.2

8.0

*

127.0

158.7

10.5

437.8

SF

132.1

84.0

9.3

*

113.6

150.5

5.3

399.0

LC

208.7

89.9

8.0

*

192.8

224.5

35.0

462.0

 

Total

166.8

91.9

5.2

 

156.5

177.1

5.3

462.0

Total prescription dose/starting dose

FC

0.6

0.4

0.0

*

0.6

0.7

0.0

2.0

SF

1.1

0.7

0.1

*

1.0

1.3

0.0

3.4

LC

1.8

0.8

0.1

*

1.7

1.9

0.3

4.0

 

Total

1.2

0.8

0.0

 

1.2

1.3

0.0

4.0

Phosphate change rate (%) [(Pi_end − Pi_week_0) × 100/Pi_week_0]

FC

2.9

31.5

3.1

 

−3.4

9.1

−45.1

116.3

SF

−10.8

22.6

2.5

*

−15.8

−5.9

−54.0

48.8

LC

−3.2

27.8

2.5

 

−8.1

1.7

−59.5

152.4

 

Total

−3.3

28.3

1.6

 

−6.4

−0.1

−59.5

152.4

Number of times ferritin ≥300 ng/mL

FC

0.1

0.4

0.0

 

0.0

0.2

0.0

4.0

SF

2.3

1.5

0.2

*

1.9

2.6

0.0

5.0

LC

0.0

0.2

0.0

 

0.0

0.1

0.0

2.0

 

Total

0.6

1.3

0.1

 

0.5

0.8

0.0

5.0

Total amount of ESA dose (μg) #

FC

440.0

567.6

56.5

 

327.9

552.0

0.0

3960.0

SF

265.7

339.2

37.5

*

191.2

340.2

0.0

1880.0

LC

424.7

445.4

39.7

 

346.2

503.2

0.0

2640.0

 

Total

387.5

469.9

26.7

 

334.9

440.1

0.0

3960.0

  1. Total amount of ESA dose was calculated using an epoetin:darbepoetin:CERA conversion ratio of 200:1:1
  2. SD standard deviation, SE standard error
  3. *used as indicators for p values