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Table 1 Clinical characteristics according to tertiles of mean rCUC

From: Positive association of residual kidney function with hemoglobin level in patients on peritoneal dialysis independent of endogenous erythropoietin concentration

  Total (N = 50) T1 (mean rCUC < 11.7 L/week/1.73m2), n = 17 T2 (mean rCUC 11.8–29.8 L/week/1.73m2), n = 17 T3 (mean rCUC ≥ 29.9 L/week/1.73m2), n = 16 P for trend
Male sex, n (%) 37 (74.0) 12 (70.6) 11 (64.7) 14 (87.5) 0.277
Age, years 54 ± 14 53 ± 14 55 ± 15 55 ± 15 0.499
Dialysis duration, months 20.2 ± 11.6 23.4 ± 12.3 18.1 ± 9.7 18.8 ± 12.5 0.213
Original disease
 DN, n (%) 16 (32.0) 7 (41.2) 6 (35.3) 3 (18.8) 0.167
 Non-DN, n (%) 34 (68.0) 10 (58.8) 11 (64.7) 13 (81.2)
Blood pressure, mmHg
 Systolic 139 ± 14 141 ± 11 137 ± 18 139 ± 13 0.845
 Diastolic 81 ± 11 82 ± 9 78 ± 16 82 ± 7 0.581
Daily alcohol consumption, n (%) 20 (40.0) 5 (29.4) 8 (47.1) 7 (43.8) 0.394
Current smoker, n (%) 9 (18.0) 3 (17.7) 2 (11.8) 4 (25.0) 0.593
Past histories of CVD, n (%) 8 (16.0) 2 (11.8) 4 (23.5) 2 (12.5) 0.939
History of peritonitis, n (%) 8 (16.0) 1 (5.9) 3 (17.7) 4 (25.0) 0.133
Body mass index, kg/m2 22.9 ± 2.9 22.4 ± 2.4 22.1 ± 2.7 24.2 ± 3.2 0.124
CTR, % 48.2 ± 5.4 49.8 ± 4.7 48.3 ± 4.6 46.6 ± 6.7 0.075
Dialysis modality
 APD, n (%) 22 (44.0) 11 (64.7) 8 (47.1) 9 (56.3) 0.614
 CAPD, n (%) 28 (56.0) 6 (35.3) 9 (52.9) 7 (43.7)
Use of icodextrin, n (%) 41 (82.0) 16 (94.1) 13 (76.5) 12 (75.0) 0.150
Use of HG dialysate, n (%) 17 (34.0) 11 (64.7) 4 (23.5) 2 (12.5) 0.002
Dose of ESA, μg/week 34 ± 18 37 ± 16 32 ± 16 31 ± 23 0.206
Total Kt/V, /week 1.71 ± 0.34 1.66 ± 0.42 1.61 ± 0.31 1.87 ± 0.23 0.011
Renal Kt/V, /week 0.46 ± 0.37 0.10 ± 0.11 0.42 ± 0.18 0.88 ± 0.27 < 0.001
Peritoneal Kt/V, /week 1.25 ± 0.38 1.56 ± 0.41 1.19 ± 0.21 0.99 ± 0.22 < 0.001
Renal Ccr, L/week, /week 29.2 ± 26.9 5.1 ± 4.9 27.4 ± 8.9 56.8 ± 27.8 < 0.001
Urine volume, L/day 0.80 ± 0.64 0.22 ± 0.24 0.76 ± 0.38 1.44 ± 0.55 < 0.001
Mean rCUC, L/week/1.73m2 22.7 ± 19.4 4.2 ± 4.2 20.5 ± 6.2 44.5 ± 16.5 < 0.001
D/Pcr 0.73 ± 0.16 0.76 ± 0.16 0.72 ± 0.17 0.70 ± 0.16 0.328
Prescriptions, n (%)
 RAS inhibitors 48 (96.0) 17 (100.0) 15 (88.2) 16 (100) 0.972
 Calcium channel blockers 37 (74.0) 15 (88.2) 10 (58.8) 12 (75.0) 0.370
β blockers 23 (46.0) 11 (64.7) 6 (35.3) 6 (37.5) 0.113
 Calcium-containing PBs 44 (88.0) 13 (76.5) 16 (94.1) 15 (93.8) 0.123
 Non-calcium containing PBs 29 (58.0) 14 (82.4) 6 (35.3) 9 (56.3) 0.119
 Iron preparations 11 (22.5) 7 (41.2) 2 (11.8) 2 (13.3) 0.054
 Vitamin D 27 (54.0) 9 (52.9) 7 (41.2) 11 (68.8) 0.375
 Cinacalcet hydrochloride 4 (8.0) 1 (5.9) 1 (5.9) 2 (12.5) 0.488
  1. Values are expressed as mean ± standard deviation or number (percentage) as appropriate
  2. Abbreviations: APD automated peritoneal dialysis, CAPD continuous ambulatory peritoneal dialysis, Ccr creatinine clearance, CTR cardiothoracic ratio, CVD cardiovascular disease, DN diabetic nephropathy, D/Pcr dialysate-to-plasma creatinine ratio, ESA erythropoiesis-stimulating agent, HG high-glucose (2.5%), Kt/V urea clearance, PBs phosphate binders, RAS renin-angiotensin system, rCUC renal creatinine and urea clearance