Blood purification therapies in methotrexate-induced acute kidney injury: four case reports

Table 2 Comparison of various types of blood purification methods

	Column used	Other conditions	Average reduction rate^a
HD	PES-15Sα®	QB 150 mL/min, 4 h	58.3 ± 6.17%
HDF	PES-15Sα®	QB 200 mL/min, 4 h, (Sublood®-BSG 8 L/4 h)	40.0 ± 5.63%
HP	CHS-350®	QB 150 mL/min, 4 h	55.3 ± 11.6%
HD + HP	VPS-13HA®/PES-13Sα® (absorption column CHS-350®)	QB 80–180 mL/min, 4 h	57.9 ±10.6%

HD hemodialysis, HDF hemodialysis filtration, HP hemoperfusion, QB quantity of blood flow. PES-15Sα® and PES-13Sα® polyethersulfone dialyzer, VPS-13HA® vitamin E-coated polysulfone dialyzer, Hemosorba CHS-350® activated chacol column, Sublood®-BSG substitution fluid
^aReduction rate is calculated by dividing the difference of MTX blood concentration before and after blood purification by MTX blood concentration before blood purification

ISSN: 2059-1381