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Table 1 Clinical, biochemical, and therapeutic characteristics of the study patients

From: Effects of preoperative cinacalcet hydrochloride treatment on the operative course of parathyroidectomy and pathological changes in resected parathyroid glands

 

All (n = 194)

Non-CH group (n = 149)

CH group (n = 45)

P value

Age, years

55.3 ± 11.7

55.9 ± 11.7

53.3 ± 11.7

0.186

Female (%)

44.3

46.3

37.8

0.313

Dialysis vintage, years

13.0 ± 6.3

13.6 ± 6.4

11.1 ± 5.7

0.020

Underlying diseases (%)

 CGN

54.1

55.0

51.1

0.747

 DMn

8.8

7.4

13.3

 Nephrosclerosis

6.7

6.7

6.7

 PCK

8.8

8.1

11.1

 Others

3.6

3.4

44.4

 Unknown

18.0

19.5

13.3

WBC (/μL)

4916.6 ± 1283.2

4805.4 ± 1253.4

5284.9 ± 1325.9

0.027

Hb (g/dL)

10.6 ± 1.4

10.5 ± 1.4

10.8 ± 1.5

0.265

Plt (× 104/μL)

18. 2 ± 5.3

18.0 ± 5.1

18.8 ± 5.8

0.360

TP (g/dL)

6.3 ± 0.5

6.3 ± 0.5

6.3 ± 0.4

0.385

Alb (g/dL)

3.7 ± 0.3

3.7 ± 0.3

3.7 ± 0.3

0.183

SUN (mg/dL)

64.2 ± 16.5

64.9 ± 16.9

61.8 ± 14.9

0.286

Cr (mg/dL)

12.5 ± 3.0

12.5 ± 3.0

12.6 ± 2.9

0.841

ALP(U/L)

398.5 ± 284.3

386.1 ± 230.7

483.7 ± 413.5

0.419

corrected Ca (mg/dL)

10.1 ± 0.9

10.2 ± 0.8

9.7 ± 1.0

< 0.001

P (mg/dL)

6.3 ± 1.3

6.3 ± 1.3

6.0 ± 1.5

0.168

Intact PTH (pg/mL)

740.1 ± 408.1

764.6 ± 373.9

662.4 ± 498.5

0.210

CaCO3 (%)

47.4

45.0

55.6

0.213

(Dose g/day)

2.7 ± 1.9

2.6 ± 1.9

3.1 ± 1.7

0.252

Non-Ca containing P binders (%)

79.4

83.9

86.7

0.139

Oral VDRA (%)

4.1

4.0

4.4

0.902

Intravenous VDRA (%)

59.8

57.7

66.7

0.283

CH (%)

23.2

0

100

–

  1. Data are presented as percentage or mean ± standard deviation
  2. CGN chronic glomerulonephritis, DMn diabeteic nephropathy, PCK polycystic kidney disease, WBC white blood cell, Hb hemoglobin, Plt. Platelets, TP total protein, Alb albumin, SUN serum urea nitrogen, Cr creatinine, ALP alkaline phosphatase, Ca calcium, P phosphate, PTH parathyroid hormone, VDRA vitamin D receptor activator, CH cinacalcet hydrochloride