Table 4 The list of adverse drug reactions
2.5-μg administration period | 5-μg administration period | 5-μg administration period + follow-up period | Treatment period + follow-up period | |
|---|---|---|---|---|
N = 37 | N = 35 | N = 35 | N = 37 | |
Adverse drug reactions | Number of patients (%) | Number of patients (%) | Number of patients (%) | Number of patients (%) |
Insomnia | 3 (8.1) | 2 (5.7) | 2 (5.7) | 5 (13.5) |
Dizziness | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Hypoaesthesia | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Somnolence | 3 (8.1) | 0 (0.0) | 0 (0.0) | 3 (8.1) |
Restless legs syndrome | 0 (0.0) | 1 (2.9) | 1 (2.9) | 1 (2.7) |
Constipation | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Gastrooesophageal reflux disease | 0 (0.0) | 1 (2.9) | 1 (2.9) | 1 (2.7) |
Vomiting | 1 (2.7) | 1 (2.9) | 1 (2.9) | 2 (5.4) |
Hypoaesthesia oral | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Hepatic function abnormal | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Drug eruption | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Pruritus | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Rash | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Haematuria | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Asthenia | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Feeling hot | 1 (2.7) | 0 (0.0) | 0 (0.0) | 1 (2.7) |
Aspartate aminotransferase increased | 0 (0.0) | 0 (0.0) | 1 (2.9) | 1 (2.7) |
Blood prolactin increased | 2 (5.4) | 2 (5.7) | 3 (8.6) | 5 (13.5) |
Blood testosterone free decreased | 2 (5.4) | 1 (2.9) | 1 (2.9) | 3 (8.1) |