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Table 2 Significant independent factors associated with all-cause mortality in stable hemodialysis patients

From: Low serum sodium concentration is a prognostic factor related to current blood glucose level in stable hemodialysis patients: an observational study

 

Univariate

Multivariate (full model)

Multivariate (final model)

Variable

HR

95% CI

P

HR

95% CI

P

HR

95% CI

P

Age (per 1 year)

1.089

1.074–1.104

< 0.001

1.100

1.081–1.119

< 0.001

1.098

1.081–1.116

< 0.001

Gender (vs. female)

1.768

1.289–2.425

< 0.001

1.702

1.172–2.471

0.005

1.759

1.264–2.449

0.001

DN (vs. non-DN)

2.149

1.583–2.915

< 0.001

1.687

1.190–2.392

0.003

1.673

1.184–2.363

0.004

HD duration (per 1 month)

0.999

0.997–1.001

0.269

1.003

1.001–1.005

0.002

1.003

1.001–1.005

0.002

β2M (per 1 mg/L)

1.049

1.023–1.076

< 0.001

1.061

1.033–1.089

< 0.001

1.063

1.037–1.089

< 0.001

CGR (per 1%)

0.979

0.973–0.985

< 0.001

0.980

0.973–0.988

< 0.001

0.980

0.973–0.987

< 0.001

Hemoglobin (per 1 g/dL)

0.803

0.711–0.908

< 0.001

0.866

0.760–0.987

0.032

0.852

0.753–0.964

0.011

Mean sodium (per 1 mEq/L)

0.863

0.822–0.907

< 0.001

0.929

0.885–0.974

0.002

0.919

0.878–0.963

< 0.001

Calcium (per 1 mg/dL)

1.202

0.991–1.457

0.062

1.190

0.983–1.439

0.074

1.236

1.028–1.486

0.024

Phosphate (per 1 mg/dL)

0.771

0.672–0.886

< 0.001

1.213

1.035–1.422

0.017

1.181

1.022–1.365

0.024

  1. In addition to age, gender, hemodialysis duration, and diabetic nephropathy, possible factors that showed P less than 0.15 in univariate analysis such as Kt/V, β2-microglobulin, protein catabolic rate, creatinine generation rate, hemoglobin, platelet, albumin, uric acid, mean sodium, potassium, calcium, phosphate, and mean interdialytic weight gain were chosen in full-model analysis
  2. Final model analysis was done with age, gender, hemodialysis duration, diabetic nephropathy, and the variables with P less than 0.1 in full-model analysis such as β2-microglobulin, creatinine generation rate, hemoglobin, mean sodium, calcium, and phosphate
  3. DN diabetic nephropathy, HD duration hemodialysis duration, β 2 M cumulative mean predialysis β2-microglobulin, CGR creatinine generation rate, HR hazard ratio, 95% CI 95% confidence interval
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Renal Replacement Therapy

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