Skip to main content

Table 2 Significant independent factors associated with all-cause mortality in stable hemodialysis patients

From: Low serum sodium concentration is a prognostic factor related to current blood glucose level in stable hemodialysis patients: an observational study

  Univariate Multivariate (full model) Multivariate (final model)
Variable HR 95% CI P HR 95% CI P HR 95% CI P
Age (per 1 year) 1.089 1.074–1.104 < 0.001 1.100 1.081–1.119 < 0.001 1.098 1.081–1.116 < 0.001
Gender (vs. female) 1.768 1.289–2.425 < 0.001 1.702 1.172–2.471 0.005 1.759 1.264–2.449 0.001
DN (vs. non-DN) 2.149 1.583–2.915 < 0.001 1.687 1.190–2.392 0.003 1.673 1.184–2.363 0.004
HD duration (per 1 month) 0.999 0.997–1.001 0.269 1.003 1.001–1.005 0.002 1.003 1.001–1.005 0.002
β2M (per 1 mg/L) 1.049 1.023–1.076 < 0.001 1.061 1.033–1.089 < 0.001 1.063 1.037–1.089 < 0.001
CGR (per 1%) 0.979 0.973–0.985 < 0.001 0.980 0.973–0.988 < 0.001 0.980 0.973–0.987 < 0.001
Hemoglobin (per 1 g/dL) 0.803 0.711–0.908 < 0.001 0.866 0.760–0.987 0.032 0.852 0.753–0.964 0.011
Mean sodium (per 1 mEq/L) 0.863 0.822–0.907 < 0.001 0.929 0.885–0.974 0.002 0.919 0.878–0.963 < 0.001
Calcium (per 1 mg/dL) 1.202 0.991–1.457 0.062 1.190 0.983–1.439 0.074 1.236 1.028–1.486 0.024
Phosphate (per 1 mg/dL) 0.771 0.672–0.886 < 0.001 1.213 1.035–1.422 0.017 1.181 1.022–1.365 0.024
  1. In addition to age, gender, hemodialysis duration, and diabetic nephropathy, possible factors that showed P less than 0.15 in univariate analysis such as Kt/V, β2-microglobulin, protein catabolic rate, creatinine generation rate, hemoglobin, platelet, albumin, uric acid, mean sodium, potassium, calcium, phosphate, and mean interdialytic weight gain were chosen in full-model analysis
  2. Final model analysis was done with age, gender, hemodialysis duration, diabetic nephropathy, and the variables with P less than 0.1 in full-model analysis such as β2-microglobulin, creatinine generation rate, hemoglobin, mean sodium, calcium, and phosphate
  3. DN diabetic nephropathy, HD duration hemodialysis duration, β 2 M cumulative mean predialysis β2-microglobulin, CGR creatinine generation rate, HR hazard ratio, 95% CI 95% confidence interval