Table 5 Demographic and clinical characteristics of NV non-responders and responders
NV non-responders | NV responders | P | |
|---|---|---|---|
Patients (n) | 12 | 6 | |
Age (years) | 60.8 ± 11.6 | 64.7 ± 1.8 | 0.43 |
Female (%) | 3 (25%) | 3 (50%) | 0.31 |
Dialysis vintage (years) | 7.0 ± 4.1 | 14.0 ± 3.5 | < 0.01 |
Antihypertensive drug users (%) | 10 (83%) | 5 (83%) | 1 |
ARB (3) | ARB (3) | ||
Ca antag. (8) | Ca antag. (3) | ||
β blocker (1) | β blocker (2) | ||
α blocker (0) | α blocker (1) | ||
αβ blocker (1) | αβ blocker (0) | ||
Antiplatelet/anticoagulant users (%)a | 7 (70%) | 5 (100%) | 0.49 |
Aspirin (6) | Aspirin (4) | ||
Clopidogrel (1) | Clopidogrel (0) | ||
Warfarin (0) | Warfarin(0) | ||
EPA (0) | EPA(0) | ||
O3FAE (0) | O3FAE (0) | ||
Other (1) | Other (2) | ||
Statin (0) | Statin (1) | ||
Ejection fraction (%)a | 70.2 ± 5.5 | 71.5 ± 5.4 | 0.69 |
Comorbidities | |||
Ischemic heart disease (%)a | 2 (20%) | 3 (60%) | 0.33 |
Heart failure (%)a | 3 (30%) | 2 (40%) | 0.85 |
Cerebral infarction (%)a | 1 (10%) | 2 (40%) | 0.49 |
Cerebral hemorrhage (%)a | 0 (0%) | 0 (0%) | 1 |
BMI (kg/m2) | 25.8 ± 5.1 | 20.7 ± 4.1 | 0.05 |
White blood cell count (×103/μL) | 6.43 ± 1.73 | 6.47 ± 2.16 | 0.91 |
Hemoglobin (g/dL) | 11.5 ± 0.9 | 11.0 ± 0.3 | 0.33 |
Platelet (×104/μL) | 20.5 ± 5.9 | 20.0 ± 4.3 | 0.93 |
ESA user (%) | 67% | 50% | 0.86 |
Ferritin (ng/mL) | 77 ± 68 | 205 ± 227 | 0.08 |
Sodium (mEq/L) | 138 ± 2 | 139 ± 2 | 0.37 |
Potassium (mEq/L) | 5.5 ± 0.8 | 4.5 ± 0.9 | 0.02 |
Phosphate (mg/dL) | 6.1 ± 1.6 | 5.3 ± 1.0 | 0.24 |
Calcium (mg/dL) | 9.0 ± 0.7 | 9.4 ± 0.8 | 0.29 |
Intact PTH (ng/mL) | 148 ± 105 | 77 ± 80 | 0.17 |
Albumin (g/dL) | 3.6 ± 0.3 | 3.5 ± 0.2 | 0.55 |
Total-cholesterol (mg/dL) | 168 ± 38 | 175 ± 39 | 0.71 |
Triglyceride (mg/dL) | 127 ± 73 | 95 ± 53 | 0.53 |
HDL-cholesterol (mg/dL) | 38 ± 10 | 56 ± 13 | < 0.01 |
Ankle brachial index (right) | 1.06 ± 0.25 | 0.94 ± 0.27 | 0.40 |
Ankle brachial index (left) | 1.12 ± 0.17 | 1.10 ± 0.26 | 0.85 |
Homocysteine (nmol/mL) | 32.6 ± 16.0 | 46.4 ± 39.8 | 0.30 |
Pentosidine (μg/mL) | 0.46 ± 0.23 | 0.39 ± 0.19 | 0.54 |
hsCRP (mg/dL) | 0.17 ± 0.17 | 0.34 ± 0.17 | 0.06 |
Pentraxin 3 (ng/mL) | 3.77 ± 1.40 | 5.00 ± 2.08 | 0.15 |
Adrenaline (ng/mL) | 0.018 ± 0.009 | 0.022 ± 0.012 | 0.40 |
Noradrenaline (ng/mL) | 0.34 ± 0.21 | 0.38 ± 0.11 | 0.69 |
Dopamine (ng/mL) | 0.033 ± 0.018 | 0.043 ± 0.021 | 0.26 |
Pre-dialysis body weight (kg) | 74.4 ± 17.1 | 54.0 ± 8.6 | 0.02 |
Post-dialysis body weight (kg) | 71.1 ± 16.1 | 51.2 ± 8.8 | 0.01 |
Ultrafiltration volume (ml/session) | 3604 ± 1234 | 2693 ± 607 | 0.11 |
Cardiothoracic ratio (%) | 51.4 ± 5.1 | 48.3 ± 4.7 | 0.24 |