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Table 5 Demographic and clinical characteristics of NV non-responders and responders

From: Effects of hydrophilic polymer-coated polysulfone membrane dialyzers on intradialytic hypotension in diabetic hemodialysis patients (ATHRITE BP Study): a pilot study

  NV non-responders NV responders P
Patients (n) 12 6  
Age (years) 60.8 ± 11.6 64.7 ± 1.8 0.43
Female (%) 3 (25%) 3 (50%) 0.31
Dialysis vintage (years) 7.0 ± 4.1 14.0 ± 3.5 < 0.01
Antihypertensive drug users (%) 10 (83%) 5 (83%) 1
  ARB (3) ARB (3)  
Ca antag. (8) Ca antag. (3)
β blocker (1) β blocker (2)
α blocker (0) α blocker (1)
αβ blocker (1) αβ blocker (0)
Antiplatelet/anticoagulant users (%)a 7 (70%) 5 (100%) 0.49
  Aspirin (6) Aspirin (4)  
Clopidogrel (1) Clopidogrel (0)
Warfarin (0) Warfarin(0)
EPA (0) EPA(0)
O3FAE (0) O3FAE (0)
Other (1) Other (2)
Statin (0) Statin (1)
Ejection fraction (%)a 70.2 ± 5.5 71.5 ± 5.4 0.69
Comorbidities
 Ischemic heart disease (%)a 2 (20%) 3 (60%) 0.33
 Heart failure (%)a 3 (30%) 2 (40%) 0.85
 Cerebral infarction (%)a 1 (10%) 2 (40%) 0.49
 Cerebral hemorrhage (%)a 0 (0%) 0 (0%) 1
BMI (kg/m2) 25.8 ± 5.1 20.7 ± 4.1 0.05
White blood cell count (×103/μL) 6.43 ± 1.73 6.47 ± 2.16 0.91
Hemoglobin (g/dL) 11.5 ± 0.9 11.0 ± 0.3 0.33
Platelet (×104/μL) 20.5 ± 5.9 20.0 ± 4.3 0.93
ESA user (%) 67% 50% 0.86
Ferritin (ng/mL) 77 ± 68 205 ± 227 0.08
Sodium (mEq/L) 138 ± 2 139 ± 2 0.37
Potassium (mEq/L) 5.5 ± 0.8 4.5 ± 0.9 0.02
Phosphate (mg/dL) 6.1 ± 1.6 5.3 ± 1.0 0.24
Calcium (mg/dL) 9.0 ± 0.7 9.4 ± 0.8 0.29
Intact PTH (ng/mL) 148 ± 105 77 ± 80 0.17
Albumin (g/dL) 3.6 ± 0.3 3.5 ± 0.2 0.55
Total-cholesterol (mg/dL) 168 ± 38 175 ± 39 0.71
Triglyceride (mg/dL) 127 ± 73 95 ± 53 0.53
HDL-cholesterol (mg/dL) 38 ± 10 56 ± 13 < 0.01
Ankle brachial index (right) 1.06 ± 0.25 0.94 ± 0.27 0.40
Ankle brachial index (left) 1.12 ± 0.17 1.10 ± 0.26 0.85
Homocysteine (nmol/mL) 32.6 ± 16.0 46.4 ± 39.8 0.30
Pentosidine (μg/mL) 0.46 ± 0.23 0.39 ± 0.19 0.54
hsCRP (mg/dL) 0.17 ± 0.17 0.34 ± 0.17 0.06
Pentraxin 3 (ng/mL) 3.77 ± 1.40 5.00 ± 2.08 0.15
Adrenaline (ng/mL) 0.018 ± 0.009 0.022 ± 0.012 0.40
Noradrenaline (ng/mL) 0.34 ± 0.21 0.38 ± 0.11 0.69
Dopamine (ng/mL) 0.033 ± 0.018 0.043 ± 0.021 0.26
Pre-dialysis body weight (kg) 74.4 ± 17.1 54.0 ± 8.6 0.02
Post-dialysis body weight (kg) 71.1 ± 16.1 51.2 ± 8.8 0.01
Ultrafiltration volume (ml/session) 3604 ± 1234 2693 ± 607 0.11
Cardiothoracic ratio (%) 51.4 ± 5.1 48.3 ± 4.7 0.24
  1. ARB angiotensin receptor blocker, Ca antag. calcium antagonist, EPA epadel, O3FAE omega-3-fatty acid ethyl esters, Other other antiplatelet/anticoagulant, BMI body mass index, ESA erythropoiesis-stimulating agent, HDL high-density lipoprotein, hsCRP high-sensitivity C-reactive protein
  2. a n = 10 in NV non-responders and n = 5 in NV responders