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Table 5 ORs of dementia with covariates

From: Is hemodialysis itself a risk factor for dementia? An analysis of nationwide registry data of patients on maintenance hemodialysis in Japan

Covariates

Number of patients

Incident number*

OR for development of dementia

 

( 95% CI )

 

p value

Covariates

Number of patients

Incident number*

OR for development of dementia

 

( 95% CI )

 

p value

Age

          

History of myocardial infarction

         
 

For every 10 years old

120,101

4031

1.05

(

1.02

1.07

)

0.0003

 

No

113,283

3762

1.00

 

Reference

  

Sex

           

Yes

6610

265

1.02

(

0.91

1.14

)

0.7

 

Male

74,472

2112

1.00

 

Reference

   

No information available

208

4

0.61

(

0.30

1.25

)

0.2

 

Female

45,629

1919

1.14

(

1.08

1.21

)

0.0001

History of limb amputation

         

Comorbidity of diabetes

          

No

117,449

3911

1.00

 

Reference

  
 

Without diabetes

80,207

2439

1.00

 

Reference

   

Yes

2455

111

0.66

(

0.56

0.77

)

0.0001

 

With diabetes

39,894

1592

1.00

(

0.94

1.07

)

0.9

 

No information available

197

9

1.03

(

0.53

2.00

)

0.9

Kt/V

          

History of hip fracture

         
 

For every 0.1 increase

112,533

3690

1.00

(

0.99

1.01

)

0.5

 

No

117,467

3789

1.00

 

Reference

  
 

No information available

7568

341

1.00

(

0.83

1.19

)

1.0

 

Yes

2121

219

2.38

(

2.10

2.71

)

0.0001

Body mass index

          

No information available

513

23

1.26

(

0.82

1.93

)

0.3

 

For every 1 kg/m2 increase

105,234

3390

0.99

(

0.98

1.00

)

0.2

Activities of daily living

         
 

No information available

14,867

641

1.01

(

0.81

1.25

)

1.0

 

No symptoms

66,253

1009

1.00

 

Reference

  

Serum albumin level

          

Moderate symptoms

37,309

1159

1.13

(

1.05

1.22

)

0.001

 

For every 1.0 g/dl increase

116,318

3923

0.96

(

0.89

1.04

)

0.3

 

≥ 50% sitting up§

10,184

1050

4.49

(

4.14

4.88

)

0.0001

 

No information available

3783

108

0.76

(

0.55

1.06

)

0.1

 

≥ 50% in bed#

3680

548

9.60

(

8.69

10.6

)

0.0001

CRP level

          

Whole day in bed

1132

224

21.70

(

18.7

25.2

)

0.0001

 

For every 1.0 mg/dl increase

58,498

2276

1.02

(

1.00

1.04

)

0.03

 

No information available

1543

41

0.95

(

0.66

1.37

)

0.8

 

No information available

61,603

1755

0.94

(

0.88

1.02

)

0.1

Place of residence

         

Hemoglobin level

          

Homes

114,690

3286

1.00

 

Reference

  
 

For every 1.0 g/dl increase

118,829

3967

0.99

(

0.97

1.01

)

0.5

 

Care facilities^

1109

191

10.95

(

9.53

12.6

)

0.0001

 

No information available

1272

64

1.18

(

0.84

1.65

)

0.3

 

Hospitals

3393

526

5.32

(

4.86

5.84

)

0.0001

            

No information available

909

28

1.15

(

0.73

1.82

)

0.5

  1. The associations between the covariates and dementia risk, which were obtained from the whole patient group analysis using a multifactor model, are shown
  2. ADLs activities of daily living, CI confidence interval, CRP C-reactive protein, OR odds ratio
  3. *Number of patients with dementia
  4. No symptoms (the patient can perform social activities without symptoms and behave without restrictions)
  5. Moderate symptoms (the patient has mild symptoms and has trouble with physical work, but can walk and do light and sedentary work, such as light domestic and clerical work)
  6. §≥ 50% sitting up (the patient can walk and take care of him/herself, but sometimes requires care. The patient can sit up at least half of the day, but cannot do light work)
  7. #≥ 50% in bed (the patient can take care of him/herself to some extent, but often requires care and is in bed at least half of the day)
  8. Whole day in bed (the patient cannot take care of him/herself and requires constant care. The patient must be in bed all day)
  9. Patients’ own home
  10. ^Care facilities (e.g., homes with care services; nursing homes, such as private nursing homes without national aid and nursing homes for families with financial difficulties; group homes; vocational centers; or relief facilities)
  11. Hospitals (e.g., health service facilities for the elderly; beds for general patients, patients at chronic stage, patients requiring rehabilitation, and patients with mental illness and infectious diseases, such as tuberculosis)