From: l-carnitine in critically ill patients—a case series study
Carnitine elevation group (n = 14) | Carnitine reduction group (n = 15) | p value | |
---|---|---|---|
f-Carnitine‡ change from day 0 to day 14 (Δf-Carnitine‡) | 12.2 (4.7~26.9) | − 22.3 (− 34.8~− 4.4) | < 0.01 |
Age | 64.2 ± 17.0 | 61.8 ± 11.5 | 0.66 |
Body mass index | 22.4 ± 2.8 | 19.4 ± 2.9 | 0.01 |
ICU duration | 7.5 (3.0~13.7) | 12.0 (5.0~21.0) | 0.14 |
Sepsis during ICU stay | 6 (40.0) | 6 (42.8) | 0.87 |
APACHE II¶ score on admission | 26.6 ± 8.7 | 29.4 ± 8.8 | 0.40 |
SOFA§ score on admission | 8.0 ± 3.6 | 9.0 ± 4.6 | 0.53 |
Mechanical ventilation during ICU stay | 0.0 (0.0~2.0) | 4.0 (0.0~8.0) | 0.08 |
Artificial nutrition at day 14 | 7 (42.8) | 8 (53.3) | 1.0 |
Parenteral nutrition at day 14 | 3 (21.4) | 0 (0) | 0.1 |
Enteral nutrition at day 14 | 4 (28.5) | 8 (53.3) | 0.26 |
Calorie intake per weight at day 14 | 26.4 ± 9.2 | 28.8 ± 8.4 | 0.46 |
Renal replacement therapy during ICU stay | 6 (42.8) | 9 (60.0) | 0.46 |