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Table 2 Univariate cox proportional hazards regression analysis of mortality

From: Asymptomatic peripheral artery disease and mortality in patients on hemodialysis

Parameter

Univariate analysis

Hazard ratio (95% CI)

P value

PAD

  

 Non-PAD

Reference

 

 Total PAD (vs. non-PAD)

3.040

(1.816 to 5.089)

< 0.001

 Asymptomatic PAD (vs. non-PAD)

2.809

(1.559 to 5.059)

0.001

 Symptomatic PAD (vs. non-PAD)

3.515

(1.755 to 7.041)

< 0.001

Age, per 1 year

1.067

(1.040 to 1.095)

< 0.001

Male vs. female

1.637

(0.938 to 2.855)

0.083

Body mass index, per 1 kg/m2

0.897

(0.824 to 0.977)

0.012

Dialysis vintage, per 1 year

1.009

(0.981 to 1.038)

0.541

Cause of ESRD

 

0.010

 Glomerulonephritis

Reference

 

 Diabetic nephropathy

1.624

(0.767 to 3.440)

0.205

 Hypertension

4.782

(2.066 to 11.069)

< 0.001

 Cystic disease

1.642

(0.364 to 7.419)

0.519

 Other

1.912

(0.792 to 4.614)

0.149

 Unknown

2.794

(1.083 to 7.208)

0.034

Diabetes

1.033

(0.607 to 1.755)

0.906

Coronary artery disease

1.183

(0.598 to 2.337)

0.630

Cerebrovascular disease

2.040

(1.146 to 3.630)

0.015

Smoking status (ever vs. never)

1.305

(0.764 to 2.231)

0.329

Creatinine, per 1 mEq/L

0.842

(0.763 to 0.929)

0.001

Albumin, per 1 g/dL

0.138

(0.068 to 0.280)

< 0.001

Hemoglobin, per 1 g/dL

0.887

(0.679 to 1.159)

0.380

HDL-C, per 1 mg/dL

0.988

(0.968 to 1.008)

0.227

GNRI

0.220

(0.074 to 0.683)

0.009

  1. Analyses were performed using cox proportional hazards regression (unadjusted for background factors on survival)
  2. PAD peripheral artery disease, ESRD end-stage renal disease, HDL-C high-density lipoprotein cholesterol, GNRI geriatric nutritional risk index, CI confidence interval