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Table 1 Patient baseline characteristics and comparison between groups with 5D-J score ≥ 9 and ≤ 8

From: Usefulness of the Japanese version of the 5-D itch scale for rating pruritus experienced by patients undergoing hemodialysis

  Total (n = 336) 5D-J total scores  
Number (%) ≥ 9 (n = 145) number (%) ≤ 8 (n = 191) number (%) p value
Male/female 213 (63.4)/123 (36.6) 93 (64.1)/52 (35.9) 120 (62.8)/71 (37.2) 0.801*
Median, IQR age (years) 70, 63–77 71, 61–78 69, 62–77 0.226**
Median, IQR duration of hemodialysis (months) 66, 33–131 67, 38–119 64, 27–151 0.889**
Primary illness of chronic kidney disease
 Diabetes mellitus 152 (45.2) 74 (51.0) 78 (40.8) 0.063*
 Chronic glomerulonephritis 87 (25.9) 33 (22.8) 54 (28.3) 0.253*
 Nephrosclerosis 35 (10.4) 14 (9.7) 21 (11.0) 0.691*
 Other 35 (10.4) 12 (8.3) 23 (12.0) 0.263*
 Unknown 27 (8.0) 12 (8.3) 15 (7.9) 0.888*
Comorbidities
 Hypertension 312 (92.9) 134 (92.4) 178 (93.2) 0.783*
 Ischemic heart disease 79 (23.5) 45 (31.0) 34 (17.8) < 0.005*
 Congestive heart failure 64 (19.1) 26 (17.9) 38 (19.9) 0.650*
 Cerebral vascular disease 85 (25.3) 41 (28.3) 44 (23.0) 0.274*
 Peripheral arterial disease 39 (11.6) 19 (13.1) 20 (10.5) 0.456*
 Chronic lung disease 24 (7.1) 12 (8.3) 12 (6.3) 0.482*
 Chronic liver disease 19 (5.7) 11 (7.6) 8 (4.2) 0.182*
 Malignant neoplasm 19 (5.7) 9 (6.2) 10 (5.2) 0.703*
Medication for pruritus
 Moisturizers 142 (42.3) 79 (54.5) 63 (33.0) < 0.001*
 Topical steroids 83 (24.7) 54 (15.2) 29 (10.0) < 0.001*
 Other topical drugs 35 (10.4) 22 (15.2) 13 (6.8) < 0.001*
 Oral antihistamines 13 (3.9) 8 (5.5) 5 (2.6) 0.172*
 Anti-allergy injections 2 (0.6) 2 (1.4) 0 (0.0) 0.186***
 Nalfurafine 39 (11.6) 19 (13.1) 20 (10.5) 0.456*
Laboratory parameters (median, IQR)
 Serum albumin (g/dL) 3.6, 3.4–3.8 3.5, 3.3–3.7 3.6, 3.4–3.8 0.070**
 Serum corrected calcium (mg/dL) 8.4, 8.1–8.8 8.9, 8.4–9.2 8.8, 8.4–9.1 0.974**
 Phosphorus (mg/dL) 4.9, 4.1–5.4 4.9, 4.1–5.4 4.9, 4.1–5.4 0.823****
 Whole PTH (pg/mL) 76.4, 51.7–116.2 79.2, 56.7–124.7 71.9, 47.2–109.7 0.101**
 Hemoglobin (g/dL) 11.3, 10.7–11.9 11.2, 10.7–11.8 11.4, 10.7–11.9 0.283**
 β2-microglobulin (mg/L) 22.9, 20.0–26.4 23.1, 20.4–27.0 22.8, 19.6–25.9 0.174**
 Kt/V 1.5, 1.4–1.6 1.5, 1.4–1.6 1.5, 1.4–1.6 0.801**
  1. Data are presented as n (%), unless stated otherwise. p values were calculated using χ2 test*, Mann-Whitney U test**, Fisher’s exact test***, and Student’s t test****, respectively