Table 1 Patient baseline characteristics and comparison between groups with 5D-J score ≥ 9 and ≤ 8
Total (n = 336) | 5D-J total scores | |||
|---|---|---|---|---|
Number (%) | ≥ 9 (n = 145) number (%) | ≤ 8 (n = 191) number (%) | p value | |
Male/female | 213 (63.4)/123 (36.6) | 93 (64.1)/52 (35.9) | 120 (62.8)/71 (37.2) | 0.801* |
Median, IQR age (years) | 70, 63–77 | 71, 61–78 | 69, 62–77 | 0.226** |
Median, IQR duration of hemodialysis (months) | 66, 33–131 | 67, 38–119 | 64, 27–151 | 0.889** |
Primary illness of chronic kidney disease | ||||
Diabetes mellitus | 152 (45.2) | 74 (51.0) | 78 (40.8) | 0.063* |
Chronic glomerulonephritis | 87 (25.9) | 33 (22.8) | 54 (28.3) | 0.253* |
Nephrosclerosis | 35 (10.4) | 14 (9.7) | 21 (11.0) | 0.691* |
Other | 35 (10.4) | 12 (8.3) | 23 (12.0) | 0.263* |
Unknown | 27 (8.0) | 12 (8.3) | 15 (7.9) | 0.888* |
Comorbidities | ||||
Hypertension | 312 (92.9) | 134 (92.4) | 178 (93.2) | 0.783* |
Ischemic heart disease | 79 (23.5) | 45 (31.0) | 34 (17.8) | < 0.005* |
Congestive heart failure | 64 (19.1) | 26 (17.9) | 38 (19.9) | 0.650* |
Cerebral vascular disease | 85 (25.3) | 41 (28.3) | 44 (23.0) | 0.274* |
Peripheral arterial disease | 39 (11.6) | 19 (13.1) | 20 (10.5) | 0.456* |
Chronic lung disease | 24 (7.1) | 12 (8.3) | 12 (6.3) | 0.482* |
Chronic liver disease | 19 (5.7) | 11 (7.6) | 8 (4.2) | 0.182* |
Malignant neoplasm | 19 (5.7) | 9 (6.2) | 10 (5.2) | 0.703* |
Medication for pruritus | ||||
Moisturizers | 142 (42.3) | 79 (54.5) | 63 (33.0) | < 0.001* |
Topical steroids | 83 (24.7) | 54 (15.2) | 29 (10.0) | < 0.001* |
Other topical drugs | 35 (10.4) | 22 (15.2) | 13 (6.8) | < 0.001* |
Oral antihistamines | 13 (3.9) | 8 (5.5) | 5 (2.6) | 0.172* |
Anti-allergy injections | 2 (0.6) | 2 (1.4) | 0 (0.0) | 0.186*** |
Nalfurafine | 39 (11.6) | 19 (13.1) | 20 (10.5) | 0.456* |
Laboratory parameters (median, IQR) | ||||
Serum albumin (g/dL) | 3.6, 3.4–3.8 | 3.5, 3.3–3.7 | 3.6, 3.4–3.8 | 0.070** |
Serum corrected calcium (mg/dL) | 8.4, 8.1–8.8 | 8.9, 8.4–9.2 | 8.8, 8.4–9.1 | 0.974** |
Phosphorus (mg/dL) | 4.9, 4.1–5.4 | 4.9, 4.1–5.4 | 4.9, 4.1–5.4 | 0.823**** |
Whole PTH (pg/mL) | 76.4, 51.7–116.2 | 79.2, 56.7–124.7 | 71.9, 47.2–109.7 | 0.101** |
Hemoglobin (g/dL) | 11.3, 10.7–11.9 | 11.2, 10.7–11.8 | 11.4, 10.7–11.9 | 0.283** |
β2-microglobulin (mg/L) | 22.9, 20.0–26.4 | 23.1, 20.4–27.0 | 22.8, 19.6–25.9 | 0.174** |
Kt/V | 1.5, 1.4–1.6 | 1.5, 1.4–1.6 | 1.5, 1.4–1.6 | 0.801** |