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Table 1 Characteristics of renal transplant recipients stratified into sex-specific tertiles of serum uric acid levels

From: Serum uric acid is an independent predictor of new-onset diabetes after living-donor kidney transplantation

  Tertile 1 Tertile 2 Tertile 3 P value
Type of renal failure (haemodialysis/peritoneal dialysis/preemptive) (36/9/3) (38/6/6) (38/9/6) 0.7
Sex (men/women) 27/21 26/24 31/22 0.79
Age (years) 43.3 ± 10.6 41.9 ± 13.7 38.1 ± 10.5 0.07
Family history of diabetes (%) 10.4 16.0 13.2 0.71
Smoking history (%) 66.6 44.0 54.7 0.07
Duration of dialysis (years) 3.4 ± 4.7 2.4 ± 3.4 3.0 ± 5.4 0.56
BMI (kg/m2) 20.3 ± 2.9 20.1 ± 2.8 21.3 ± 3.5 0.14
Systolic BP (mmHg) 149.3 ± 22.9 149.3 ± 21.3 154.0 ± 21.2 0.45
Diastolic BP (mmHg) 85.7 ± 13.1 84.6 ± 12.2 87.5 ± 13.9 0.51
Albumin (g/dL) 4.1 ± 0.5 3.9 ± 0.4 3.9 ± 0.4 0.17
Total cholesterol (mg/dL) 176.4 ± 37.4 171.3 ± 40.1 165.0 ± 38.5 0.33
Triglycerides (mg/dL) 171.0 ± 11.5 158.4 ± 7.4 171.0 ± 11.5 0.76
SUA (mg/dL) 5.7 ± 1.1 7.3 ± 0.4 9.4 ± 1.0 NA
SUA after transplantation(mg/dL) 6.4 ± 0.2 6.2 ± 0.2 7.2 ± 0.2 0.003
Creatinine (mg/dL) 10.2 ± 2.9 12.0 ± 2.8 12.2 ± 3.1 0.001
eGFR (mL/min/1.73 m2) 5.2 ± 2.6 4.1 ± 1.2 4.2 ± 1.5 0.01
Haemoglobin (g/dL) 10.7 ± 0.2 10.4 ± 0.1 10.3 ± 0.1 0.36
HbA1c (%) 5.3 ± 0.4 5.2 ± 0.4 5.3 ± 0.5 0.67
HOMA-IR 1.0 ± 0.5 1.2 ± 1.0 1.4 ± 0.9 0.06
Insulinogenic index 0.7 ± 0.4 1.0 ± 0.9 1.4 ± 2.6 0.08
Diuretics (%) 41.6 38.0 30.1 0.46
Allopurinol therapy (%) 22.9 34.0 26.4 0.45
Statin (%) 10.4 8.0 13.2 0.69
Antiplatelet agents (%) 14.5 26.0 11.3 0.12
RAS inhibitor (%) 47.9 48.0 50.9 0.94
CCB agents (%) 62.5 62.0 54.7 0.66
β-Blockers (%) 16.6 14.0 20.7 0.65
Calcineurin inhibitor (tacrolimus/cyclosporin A) (%) 52.0:47.9 56.0:44.0 52.8:47.1 0.91
HCV-positive (%) 2.0 2.0 9.4 0.11
  1. Cohort size n = 151 (84 men and 67 women). The statistical significance was estimated with a one-way analysis of variance and Fisher’s exact text (P < 0.05). Data are expressed as mean ± standard deviation or percent
  2. BMI body mass index, BP blood pressure, CCB calcium channel blocker, eGFR estimated glomerular filtration rate, HbA1c haemoglobin A1c, HCV hepatitis C virus, HOMA-IR homeostasis model assessment of insulin resistance, NA not applicable, RAS renin-angiotensin system, SUA serum uric acid