Table 1 Characteristics of renal transplant recipients stratified into sex-specific tertiles of serum uric acid levels
Tertile 1 | Tertile 2 | Tertile 3 | P value | |
|---|---|---|---|---|
Type of renal failure (haemodialysis/peritoneal dialysis/preemptive) | (36/9/3) | (38/6/6) | (38/9/6) | 0.7 |
Sex (men/women) | 27/21 | 26/24 | 31/22 | 0.79 |
Age (years) | 43.3 ± 10.6 | 41.9 ± 13.7 | 38.1 ± 10.5 | 0.07 |
Family history of diabetes (%) | 10.4 | 16.0 | 13.2 | 0.71 |
Smoking history (%) | 66.6 | 44.0 | 54.7 | 0.07 |
Duration of dialysis (years) | 3.4 ± 4.7 | 2.4 ± 3.4 | 3.0 ± 5.4 | 0.56 |
BMI (kg/m2) | 20.3 ± 2.9 | 20.1 ± 2.8 | 21.3 ± 3.5 | 0.14 |
Systolic BP (mmHg) | 149.3 ± 22.9 | 149.3 ± 21.3 | 154.0 ± 21.2 | 0.45 |
Diastolic BP (mmHg) | 85.7 ± 13.1 | 84.6 ± 12.2 | 87.5 ± 13.9 | 0.51 |
Albumin (g/dL) | 4.1 ± 0.5 | 3.9 ± 0.4 | 3.9 ± 0.4 | 0.17 |
Total cholesterol (mg/dL) | 176.4 ± 37.4 | 171.3 ± 40.1 | 165.0 ± 38.5 | 0.33 |
Triglycerides (mg/dL) | 171.0 ± 11.5 | 158.4 ± 7.4 | 171.0 ± 11.5 | 0.76 |
SUA (mg/dL) | 5.7 ± 1.1 | 7.3 ± 0.4 | 9.4 ± 1.0 | NA |
SUA after transplantation(mg/dL) | 6.4 ± 0.2 | 6.2 ± 0.2 | 7.2 ± 0.2 | 0.003 |
Creatinine (mg/dL) | 10.2 ± 2.9 | 12.0 ± 2.8 | 12.2 ± 3.1 | 0.001 |
eGFR (mL/min/1.73 m2) | 5.2 ± 2.6 | 4.1 ± 1.2 | 4.2 ± 1.5 | 0.01 |
Haemoglobin (g/dL) | 10.7 ± 0.2 | 10.4 ± 0.1 | 10.3 ± 0.1 | 0.36 |
HbA1c (%) | 5.3 ± 0.4 | 5.2 ± 0.4 | 5.3 ± 0.5 | 0.67 |
HOMA-IR | 1.0 ± 0.5 | 1.2 ± 1.0 | 1.4 ± 0.9 | 0.06 |
Insulinogenic index | 0.7 ± 0.4 | 1.0 ± 0.9 | 1.4 ± 2.6 | 0.08 |
Diuretics (%) | 41.6 | 38.0 | 30.1 | 0.46 |
Allopurinol therapy (%) | 22.9 | 34.0 | 26.4 | 0.45 |
Statin (%) | 10.4 | 8.0 | 13.2 | 0.69 |
Antiplatelet agents (%) | 14.5 | 26.0 | 11.3 | 0.12 |
RAS inhibitor (%) | 47.9 | 48.0 | 50.9 | 0.94 |
CCB agents (%) | 62.5 | 62.0 | 54.7 | 0.66 |
β-Blockers (%) | 16.6 | 14.0 | 20.7 | 0.65 |
Calcineurin inhibitor (tacrolimus/cyclosporin A) (%) | 52.0:47.9 | 56.0:44.0 | 52.8:47.1 | 0.91 |
HCV-positive (%) | 2.0 | 2.0 | 9.4 | 0.11 |