Skip to main content

Table 4 Result items that were evaluated for 12 months in patients who completed the study and were not withdrawn

From: The clinical evaluation of novel polymethyl methacrylate membrane with a modified membrane surface: a multicenter pilot study

Items

Baseline

3 months

6 months

9 months

12 months

NF group

PS group

NF group

PS group

NF group

PS group

NF group

PS group

NF group

PS group

Number of patients

14

17

14

17

14

17

14

17

14

17

CRP (mg/dL)

0.55 ± 0.52

0.75 ± 0.66

0.53 ± 0.60

0.99 ± 2.03

0.61 ± 0.65

0.71 ± 0.83

0.68 ± 0.88

0.62 ± 0.46

0.64 ± 0.94

0.49 ± 0.42

nPCR (g/kg/day)

0.88 ± 0.17

0.90 ± 0.15

0.89 ± 0.16

0.85 ± 0.134

0.89 ± 0.14

0.89 ± 0.16

0.91 ± 0.16

0.91 ± 0.16

0.86 ± 0.12

0.86 ± 0.17

%CGR (%)

114 ± 25

115 ± 18

117 ± 23

109 ± 21

112 ± 21

107 ± 21#

117 ± 18

108 ± 18#

119 ± 20

109 ± 24

Albumin (g/dL)

3.6 ± 0.3

3.5 ± 0.3

3.4 ± 0.4#

3.5 ± 0.3

3.4 ± 0.3#

3.6 ± 0.3

3.5 ± 0.3

3.5 ± 0.3

3.5 ± 0.3

3.5 ± 0.3

MNA-SF

13 ± 1

13 ± 1

12 ± 2

13 ± 1

13 ± 1

13 ± 2

13 ± 1

13 ± 1

12 ± 2

13 ± 1

MNA screening score (n)

 Normal nutritional status

14

16

11

16

13

15

13

14

12

13

 At risk of malnutrition

0

1

3

1

1

2

1

3

2

4

 Malnourished

0

0

0

0

0

0

0

0

0

0

Itchiness (VAS values)

22.1 ± 19.8

14.1 ± 16.6

21.6 ± 17.4

20.6 ± 19.5

27.9 ± 28.9

30.5 ± 25.6

12.1 ± 20.4$

24.7 ± 21.0

14.1 ± 23.8

19.1 ± 19.0

Body weight (kg)

61.4 ± 12.0

66.3 ± 13.4

61.5 ± 11.8

66.0 ± 12.7

61.2 ± 11.5

65.7 ± 12.3

61.0 ± 11.4

65.2 ± 12.2

60.5 ± 11.1

64.9 ± 11.9

Reduction rate of weight (%)

0.1 ± 1.7

− 0.2 ± 1.5

− 0.3 ± 1.8

− 0.6 ± 2.1

− 0.6 ± 1.9

− 1.4 ± 3.0

− 1.3 ± 1.8

− 1.6 ± 4.1

 Mild

3

6

7

6

8

6

9

5

 Moderate

0

0

0

1

0

3

0

4

 Severe

0

0

0

0

0

0

0

0

Blood cell counts

 White blood cell (/μL)

6676 ± 2115

7207 ± 1972

6536 ± 1934

6952 ± 1827

7093 ± 2164

7170 ± 2155

6783 ± 2442

7010 ± 1729

7087 ± 2278

6836 ± 2528

 Red blood cell (× 104/μL)

359 ± 29

356 ± 42

360 ± 21

355 ± 39

360 ± 37

358 ± 46

371 ± 42

353 ± 39

354 ± 42

353 ± 47

 Platelet (× 104/μL)

21.6 ± 6.7

20.7 ± 4.9

20.7 ± 5.7

19.5 ± 4.9

22.4 ± 7.3

18.9 ± 4.2#

22.3 ± 7.6

18.7 ± 4.3#

22.1 ± 6.2

19.5 ± 4.3

Dialysis dose

 Kt/V

1.50 ± 0.26

1.56 ± 0.23

1.51 ± 0.25

1.56 ± 0.22

1.52 ± 0.27

1.54 ± 0.22

1.51 ± 0.25

1.54 ± 0.21

1.51 ± 0.26

1.57 ± 0.24

  1. MNA screening score: normal nutritional status, 12–14 points; at risk of malnutrition, 8–11 points; malnourished, 0–7 points
  2. Reduction rate of weight (%): mild, 0–5%; moderate, 5–10%, severe, ≥ 10%
  3. CRP C-reactive protein, %CGR % creatinine generation rate, nPCR normalized protein catabolic rate, MNA-SF Mini nutrition Assessment-short form, VAS visual analog scale, NF Filtryzer® NF, PS polysulfone
  4. #p < 0.05 vs. baseline; $p < 0.05 vs. PS group