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Table 3 Representative randomized controlled trials for IDPN

From: A case of refeeding syndrome during intradialytic parenteral nutrition

 

FineS trial 2007

German IDPN trial 2017

Inclusion criteria

 Age

18–80 years old

> 18 years old

 Hemodialysis vintage

> 6 months

> 6 months

 BMI

< 20 kg/m2

 

 BW loss within 6 months

> 10%

 

 Serum albumin

< 3.5 g/dL

< 3.5 g/dL

 Serum prealbumin

< 30 mg/dL

< 25 mg/dL

 SGA

 

B or C

Exposure

IDPN with oral nutritional supplements for 1 year

IDPN (3 times per week) with standardized nutritional counseling over 16 weeks

Comparison

Oral nutritional supplements only

Standardized nutritional counseling only

Outcome

IDPN did not have additional benefit on 2-year all-cause mortality

IDPN significantly increased prealbumin (changes in serum prealbumin from baseline to week 16) (p = 0.02)

  1. BMI body mass index, BW body weight, IBW ideal body weight, SGA subjective global assessment