From: A case of refeeding syndrome during intradialytic parenteral nutrition
FineS trial 2007 | German IDPN trial 2017 | |
---|---|---|
Inclusion criteria | ||
Age | 18–80 years old | > 18 years old |
Hemodialysis vintage | > 6 months | > 6 months |
BMI | < 20 kg/m2 | |
BW loss within 6 months | > 10% | |
Serum albumin | < 3.5 g/dL | < 3.5 g/dL |
Serum prealbumin | < 30 mg/dL | < 25 mg/dL |
SGA | B or C | |
Exposure | IDPN with oral nutritional supplements for 1 year | IDPN (3 times per week) with standardized nutritional counseling over 16 weeks |
Comparison | Oral nutritional supplements only | Standardized nutritional counseling only |
Outcome | IDPN did not have additional benefit on 2-year all-cause mortality | IDPN significantly increased prealbumin (changes in serum prealbumin from baseline to week 16) (p = 0.02) |