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Table 1 Participant characteristics

From: Using Sepsis-3 criteria to predict prognosis of patients receiving continuous renal replacement therapy for community-acquired sepsis: a retrospective observational study

Characteristic All participants (n = 64)
Age, years 66.5 (51–74.8)
Sex
 Male 45 (70.3%)
 Female 19 (29.7%)
Comorbidities
 Hypertension 36 (56.3%)
 Diabetes 14 (21.9%)
 Congestive heart failure 11 (17.2%)
 Liver disease 15 (23.4%)
 Smoking 33 (51.6%)
 Alcoholism 8 (12.5%)
qSOFA 1 (1–2)
SOFA 11 (8–13.8)
APACHE II 31 (24.3–36)
Time from hospitalization to start of CRRT, min 508 (243–1395)
Surgery before the start of CRRT* 18 (28.1%)
Antimicrobial therapy before hospitalization 33 (51.6%)
Positive blood cultures 20 (31.3%)
Positive cultures 27 (42.2%)
Test results at the start of CRRT
 Creatinine, mg/dL 2.78 (1.95–4.09)
 C-reactive protein, mg/dL 14.3 (8.5–26.1)
 pH 7.35 (7.29–7.40)
 Lactate, mmol/L 2.25 (1.22–4.01)
AKI at the start of CRRT 47 (73.4%)
KDIGO stage 1 23 (35.9%)
KDIGO stage 2 8 (12.5%)
KDIGO stage 3 16 (25.0%)
Catecholamine index 12 (2.9–26.8)
PMX-DHP combination 20 (31.3%)
  1. Values are expressed as numbers (proportion) or median (interquartile range)
  2. Abbreviations: SOFA Sequential Organ Failure Assessment, APACHE Acute Physiology and Chronic Health Evaluation, CRRT continuous renal replacement therapy, AKI acute kidney injury, KDIGO Kidney Disease Improving Global Outcomes, PMX-DHP polymyxin B-immobilized fiber column direct hemoperfusion
  3. *Emergency surgery to remove the source of infection as an unplanned operation
  4. Positive cultures included blood cultures, cultures using other specimens, and pre-hospital findings