Using Sepsis-3 criteria to predict prognosis of patients receiving continuous renal replacement therapy for community-acquired sepsis: a retrospective observational study

Table 1 Participant characteristics

Characteristic	All participants (n = 64)
Age, years	66.5 (51–74.8)
Sex
Male	45 (70.3%)
Female	19 (29.7%)
Comorbidities
Hypertension	36 (56.3%)
Diabetes	14 (21.9%)
Congestive heart failure	11 (17.2%)
Liver disease	15 (23.4%)
Smoking	33 (51.6%)
Alcoholism	8 (12.5%)
qSOFA	1 (1–2)
SOFA	11 (8–13.8)
APACHE II	31 (24.3–36)
Time from hospitalization to start of CRRT, min	508 (243–1395)
Surgery before the start of CRRT*	18 (28.1%)
Antimicrobial therapy before hospitalization	33 (51.6%)
Positive blood cultures	20 (31.3%)
Positive cultures ^†	27 (42.2%)
Test results at the start of CRRT
Creatinine, mg/dL	2.78 (1.95–4.09)
C-reactive protein, mg/dL	14.3 (8.5–26.1)
pH	7.35 (7.29–7.40)
Lactate, mmol/L	2.25 (1.22–4.01)
AKI at the start of CRRT	47 (73.4%)
KDIGO stage 1	23 (35.9%)
KDIGO stage 2	8 (12.5%)
KDIGO stage 3	16 (25.0%)
Catecholamine index	12 (2.9–26.8)
PMX-DHP combination	20 (31.3%)

Values are expressed as numbers (proportion) or median (interquartile range)
Abbreviations: SOFA Sequential Organ Failure Assessment, APACHE Acute Physiology and Chronic Health Evaluation, CRRT continuous renal replacement therapy, AKI acute kidney injury, KDIGO Kidney Disease Improving Global Outcomes, PMX-DHP polymyxin B-immobilized fiber column direct hemoperfusion
*Emergency surgery to remove the source of infection as an unplanned operation
^†Positive cultures included blood cultures, cultures using other specimens, and pre-hospital findings

ISSN: 2059-1381