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Table 2 Clinical characteristics of patients who did or did not receive antiplatelet agents

From: Patency with antiplatelet treatment after vascular access intervention therapy: a retrospective observational study

 

Antiplatelet group

Non-antiplatelet group

p value

Number

31

28

 

Age

73 (68–78)

71 (58.5–80)

0.27

Older age (%)

54.8

42.9

0.44

Sex (male, %)

80.7

64.3

0.22

Etiology of ESRD (%)

 DN

48.4

32.1

0.20

 NS

25.8

21.4

0.69

 CGN

9.7

21.4

0.21

 ADPKD

3.2

0

0.34

 IgAN

6.5

3.6

0.62

 Other or unknown

6.5

21.4

0.093

Smoking history (%)

80.7

46.4

0.008

DM (%)

61.3

53.6

0.60

Dyslipidemia (%)

74.2

39.3

0.009

CVD (%)

80.7

25.0

< 0.001

 IHD

58.1

10.7

< 0.001

 CHF

16.1

10.7

0.54

 Stroke

22.6

0

0.007

PAD (%)

22.6

3.6

0.55

RASI (%)

45.2

60.7

0.30

Statin (%)

29.0

75.0

< 0.001

Warfarin (%)

6.5

10.7

0.67

ESA

 Epoetin α or β (IU/week)

3750.0 ± 1068.5

2750.0 ± 975.4

0.51

 Darbepoetin α (μg/week)

33.1 ± 9.7

47.4 ± 9.4

0.29

 CERA (μg/2 week)

50

75

Hb (g/dl)

10.6 ± 0.3

10.1 ± 0.29

0.28

Platelet (× 103/μl)

19.8 ± 1.2

17.9 ± 1.3

0.28

PT-INR

1.0 ± 0.1

1.1 ± 0.1

0.50

CRP (mg/dl)

0.6 ± 0.3

0.8 ± 0.3

0.71

Dialysis duration (month)

31.8 ± 33.2

20.8 ± 27.0

0.42

AVF anastomosis type (%)

 Radiocephalic

71.0

92.9

0.031

 Brachiocephalic

25.8

7.1

0.056

 Radiobasilic

3.2

0

0.34

Quantity of blood flow (ml/min)

194.1 ± 6.5

190 ± 7.6

0.69

Flow volume (ml/min)

 Before VAIVT

461.8 ± 86.1

373.1 ± 88.5

0.47

 After VAIVT

816.2 ± 172.9

872.1 ± 177.9

0.82

VAF

 Thrombosis (%)

19.4

10.7

0.48

Adverse event (%)

 Serious bleeding event

  Intracranial

0

0

  Gastrointestinal

0

0

 CVD event after VAIVT

  IHD

19.4

3.6

0.061

  CHF

6.5

3.6

0.62

  Stroke

3.2

0

0.34

  1. We defined individuals aged > 71 years as “the older age”
  2. ESRD end-stage renal disease, DN diabetic nephropathy, NS nephrosclerosis, CGN chronic glomerulonephritis, ADPKD autosomal dominant polycystic kidney disease, IgAN IgA nephropathy, DM diabetes mellitus, CVD cardiovascular disease, IHD ischemic heart disease, CHF congestive heart failure, PAD peripheral artery disease, RASI renin–angiotensin–aldosterone system inhibitor, ESA erythropoiesis-stimulating agent, CERA continuous erythropoietin receptor activator, AVF arteriovenous fistula, VAIVT vascular access intervention therapy, VAF vascular access failure