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Table 2 The demographics of patients with previous DAA treatment failure and other baseline clinical characteristics

From: Glecaprevir and pibrentasvir combination therapy for hepatitis C virus-infected Japanese patients on hemodialysis

Case

Duration span (weeks)

Genotype

Liver cirrhosis

Previous DAA treatment

L31

Y93

D168

SVR 12

Discontinuation therapy

Adverse events

1

8

2a

     

+

  

2

12

1b

+

DCV+ASV

L31 V>M>L

Y93 H

D168 E

+

 

Pruritus

3

8

2a

     

+

 

Pruritus

4

8

1b

  

Wild

Wild

Wild

+

  

5

8

2b

     

+

  

6

8

1b

  

Wild

Wild

Wild

+

 

Pruritus

7

12

2a

+

    

+

 

Pruritus, fatigue

8

8

2a

     

+

  

9

8

2b

     

+

  

10

12

1b

+

DCV+ASV

L31 M

Y93 H

D168 D>E

+

  

11

8

1b

  

Wild

Wild

Wild

+

  

12

12

1b

+

 

Wild

Wild

Wild

+

Weeks 8 (pruritus)

Bloating, pruritus

13

12

1b

 

DCV+ASV

L31 M

Y93 H

D168E

+

Weeks 6 (cellulitis)

Cellulitis

14

8

1b

  

Wild

Wild

Wild

+

  

15

8

2a

     

+

 

Pruritus

16

8

2b

     

Relapse

  

17

8

2a

     

+

 

Headache

18

8

1b

  

Wild

Wild

Wild

+

 

Pruritus

  1. DCV daclatasvir, ASV asunaprevir