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Table 1 Clinical characteristics of the patients

From: Carnitine deficiency is associated with decreased exercise activity in hemodialysis patients

No. of patients

37

Age (years)

55.9 ± 13.4

Sex (no.) (male/female)

24/13

HD duration (months)

153 ± 67

BMI (kg/m2)

22.5 ± 4.1

Hemoglobin (g/dl)

11.7 ± 1.5

Serum albumin (g/dl)

3.59 ± 0.24

AST (U/l)

13.6 ± 7.6

ALT (U/l)

11.9 ± 7.6

BUN (mg/dl)

60.4 ± 14.2

Serum Cr (mg/dl)

12.3 ± 2.3

Uric acid (mg/dl)

7.4 ± 1.5

Corrected Ca (mg/dl)

8.7 ± 0.6

Phosphate (mg/dl)

5.1 ± 1.3

Total chol (mg/dl)

155.0 ± 29.9

HDL-chol (mg/dl)

46.5 ± 13.5

LDL-chol (mg/dl)

84.5 ± 21.2

Triglycerides (mg/dl)

123.6 ± 94.3

CRP (mg/dl)

0.18 ± 0.29

Whole-PTH (pg/ml)

131.3 ± 93.9

NT-pro BNP (pg/ml)

4794 ± 6125

Kt/V

1.74 ± 0.35

Free carnitine (μmol/l)

24.0 ± 7.3

Total carnitine (μmol/l)

40.0 ± 11.0

Acyl carnitine (μmol/l)

16.2 ± 4.9

Primary cause of ESRD (n)

 Diabetic nephropathy

10 (27%)

 Chronic glomerulonephritis

10 (27%)

 Lupus nephritis

3 (9%)

 Focal segmental glomerulosclerosis

2 (5%)

 Hypertensive nephrosclerosis

2 (5%)

 Others

10 (27%)

Exercise examination

 TUG (s)

7.2 ± 1.8

 Knee extension strength (N/m)

27.2 ± 9.7

 Functional reach test (cm)

35.8 ± 6.7

 10 m walk test (m/sec)

8.2 ± 1.5

 Thigh circumference 10 cm (cm)

39.8 ± 3.7

 Calf circumference (cm)

33.3 ± 3.7

  1. Abbreviations: HD hemodialysis, BMI body mass index, AST aspartate transaminase, ALT alanine amino transferase, BUN blood urea nitrogen, Cr creatinine, Ca calcium, Total chol total cholesterol, HDL-chol high-density lipoprotein cholesterol, LDL-chol low-density lipoprotein cholesterol, TG triglyceride, CRP C-reactive protein, Whole PTH whole parathyroid hormone, NT-pro BNP N-terminal pro B-type natriuretic peptide, ESRD end-stage renal disease, TUG time-up-and-go test