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Table 1 Baseline characteristics of patients

From: Effect of bixalomer on coronary artery calcification in hemodialysis patients with hyperphosphatemia: a multi-center, randomized controlled trial

  Total, N = 83 Bixalomer, n = 43 Calcium carbonate, n = 40
Concomitant treatment with lanthanum carbonate 28 (33.7) 15 (34.9) 13 (32.5)
Male sex 63 (75.9) 30 (69.8) 33 (82.5)
Age (years), mean ± SD 66.0 ± 9.8 66.0 ± 9.6 66.1 ± 10.1
Height (cm), mean ± SD 160.9 ± 7.1 159.9 ± 7.1 162.0 ± 7.2
Weight (kg), mean ± SD 57.3 ± 9.6 56.1 ± 9.1 58.5 ± 10.0
Underlying disease
 Diabetic nephropathy 28 (33.7) 15 (34.9) 13 (32.5)
 Chronic glomerulonephritis 16 (19.3) 8 (18.6) 8 (20.0)
 Nephrosclerosis 17 (20.5) 11 (25.6) 6 (15.0)
 Cystic kidney 4 (4.8) 0 (0.0) 4 (10.0)
 Chronic pyelonephritis 2 (2.4) 2 (4.7) 0 (0.0)
 Other 16 (19.3) 7 (16.3) 9 (22.5)
History of dialysis (years)
 < 1 8 (9.8) 3 (7.0) 5 (12.8)
 ≥ 1, < 5 29 (35.4) 13 (30.2) 16 (41.0)
 ≥ 5, < 10 21 (25.6) 14 (32.6) 7 (17.9)a
 ≥ 10, < 15 14 (17.1) 9 (20.9) 5 (12.8)
 ≥ 15 10 (12.2) 4 (9.3) 6 (15.4)
Method of dialysis
 Hemodialysis 69 (83.1) 35 (81.4) 34 (85.0)
 Hemodiafiltration 14 (16.9) 8 (18.6) 6 (15.0)
Dialysate calcium concentration (mEq/L)
 2.5 4 (4.8) 2 (4.7) 2 (5.0)
 2.75 11 (13.3) 4 (9.3) 7 (17.5)
 3.0 68 (81.9) 37 (86.0) 31 (77.5)
 Other 0 (0.0) 0 (0.0) 0 (0.0)
Complication 81 (97.6) 42 (97.7) 39 (97.5)
 High blood pressure 65 (78.3) 36 (83.7) 29 (72.5)
 Diabetes 29 (34.9) 16 (37.2) 13 (32.5)
 Anemia in CKDb 57 (68.7) 32 (74.4) 25 (62.5)
 Secondary hyperparathyroidism 33 (39.8) 16 (37.2) 17 (42.5)
 Constipation 30 (36.1) 19 (44.2) 11 (27.5)
 Itchy skin 15 (18.1) 8 (18.6) 7 (17.5)
 Other 51 (61.4) 28 (65.1) 23 (57.5)
Combination drug 73 (88.0) 39 (90.7) 34 (85.0)
 Antihypertensive 65 (78.3) 38 (88.4) 27 (67.5)
 Drug for osteoporosis 33 (39.8) 20 (46.5) 13 (32.5)
 Drug for dyslipidemia 21 (25.3) 11 (25.6) 10 (25.0)
No combination therapyc 80 (96.4) 41 (95.3) 39 (97.5)
  1. Data are presented as n (%) unless otherwise stated
  2. aThe number of patients specifically for dialysis history in the calcium group was 39 rather than 40, as there was one patient with missing data
  3. bAnemia in CKD is defined as hemoglobin level < 11.0 g/dL or erythropoietin use in patients with CKD
  4. cPatients not receiving any therapy other than that for hemodialysis or hemodiafiltration
  5. Abbreviations: CKD chronic kidney disease, SD standard deviation