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Table 3 CAC scores at baseline, 6 months, and 12 months (during the 12-month observation period)

From: Effect of bixalomer on coronary artery calcification in hemodialysis patients with hyperphosphatemia: a multi-center, randomized controlled trial

CAC scores Baseline 6 months 12 months
Bixalomer, N 41 38 31
 Mean ± SD 947.2 ± 1013.5 1052.4 ± 1091.1 987.3 ± 1042.9
 95% CI 627.3, 1267.1 693.8, 1411.1 604.8, 1369.9
 Median 493.55 642.41 583.82
 Minimum/maximum 0/3484.5 0/3541.2 0/3830.9
Calcium carbonate, N 39 35 34
 Mean ± SD 1210.1 ± 1962.8 1367.6 ± 2131.5 1528.0 ± 2313.1
 95% CI 573.8, 1846.4 635.5, 2099.8 720.9, 2335.1
 Median 693.75 819.9 957.31
 Minimum/maximum 0/11727.9 0/12179.3 0/13070.1
Difference between groups − 262.9 − 315.2 − 540.7
 95% CI − 953.3, 427.5 − 1096.3, 465.9 − 1445.0, 363.6
P valuea 0.451 0.424 0.237
  1. aComparisons between groups were conducted using the t test
  2. Abbreviations: CAC coronary artery calcium, CI confidence interval, N number of patients, SD standard deviation