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Table 6 The association of fish oil with VAF

From: Pharmaceutical prevention strategy for arteriovenous fistula and arteriovenous graft failure

Author

Design

N (Control)

Exposure Timing

Outcome (duration)

VAF development

Schmitz et al [81]

Placebo-controlled

24 (12)

Omega-3

4 g/day

Post

Primary patency rates of AVG (1 year)

Lower risk

(75.6 % vs. 14.9%, P < 0.03)

Lok et al [80]

Placebo-controlled

201 (100)

Omega-3

4 g/day

Post

Primary AVG failure (1000 days)

Lower risk

(3.43% vs. 5.95%, HR 0.58, 95% CI 0.44–0.75, P < 0.001)

Irish et al [68]

Placebo-controlled

567 (283)

Omega-3

4 g/day

Pre

Primary AVF failure (12 months)

Equivalent risk

(22% vs. 23%, RR 0.98, 95% CI 0.72–1.34, P = 0.90)

  1. VAF vascular access failure, VA vascular access, AVF arteriovenous fistula, AVG arteriovenous graft, RR relative risk, HR hazard ratio, CI confidential interval, Pre pre-operative period, Post post-operative period