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Table 3 Patients divided into quartiles according to dialysis symptom scores. Months of dialysis treatment (vintage), ultrafiltration rate mL/kg.h (UFR), change in pre- vs post-systolic blood pressure in mmHg (SBP), dialysate temperature (Temp), dialysate sodium mmol/L (Dial Sodium), sodium gradient between serum and dialysate mmol/L (Na gradient), urea reduction (URR), % patients with recovery post-dialysis < 1 h (recovery < 1 h), C-reactive protein, glycated haemoglobin mmol/mol (HbA1c), pro N terminal brain natriuretic peptide (BNP), hand grip strength (HGS), distress thermometer (DT) and prescribed antihypertensive medications (BP meds)

From: Patient-reported intra-dialytic symptoms and post-dialysis recovery times are influenced by psychological distress rather than dialysis prescription

Variable Quartile 1 Quartile 2 Quartile 3 Quartile 4
Symptom score 5 (3–7) 17 (14–21)*** 31 (28–35)*** 51 (43–61)***
Male 79.1 68.2 49.0 44.8***
Age, years 68 ± 14 65 ± 16 65 ± 17 61 ± 17***
Diabetic, % 44.3 44.3 46.2 50.0
White, % 43.9 50.9 45.5 31.8
Black, % 37.3 28.1 27.6 36.8
Asian, % 18.9 21.0 22.5 30.5*
Vintage months 30.6 (12.5–68.8) 33.4 (10.1–70.4) 32.9 (13.6–65.7) 38.7 (18.5–71.7)
Weight, kg 73.0 ± 15.8 76.3 ± 16.0 74.3 ± 20.8 71.0 ± 20.6
% weight loss 2.2 (1.4–3.0) 2.1 (1.3–2.9) 2.2 (1.6–3.1) 2.4 (1.2–3.0)
UFR, mL/kg.h 4.2 (4.0–4.8) 4.1 (4.1–4.7) 4.1 (4.0–4.7) 4.1 (4.1–4.7)
Session hours 4.0 (3.5–4.0) 4.0 (3.5–4.0) 4.0 (3.5–4.0) 4.0 (3.5–4.0)
Temp., oC 35.9 ± 0.7 35.8 ± 0.7 35.9 ± 0.7 35.9 ± 0.7
Dial, sodium 137 ± 1.0 137 ± 1.0 137 ± 1.0 137 ± 1.0
Na, gradient 2 (0 to 4) 2 (0 to 4) 2 (− 1 to 4) 2 (− 1 to 4)
Qb, mL/min 322 ± 31 323 ± 31 320 ± 29 322 ± 39
Dialyzer, m2 1.9 ± 0.3 2.0 ± 0.3 2.0 ± 3.0 1.9 ± 0.3
URR, % 73.8 ± 8.9 71.5 ± 9.9 73.4 ± 8.5 74.5 ± 9.3
%SBP > 20 down 26.1 29.8 39 29.5
%SBP > 10 up 25.5 22.4 12.8* 14.8*
Haemoglobin, g/L 108.5 ± 14.5 108.9 ± 14.8 109.4 ± 14.5 105.5 ± 13.4
Recovery < 1 h 18.5 15.2 8.7*** 7.2***
Albumin, g/L 38.4 ± 4.5 38.5 ± 4.6 38.2 ± 4.1 38.2 ± 4.7
CRP, mg/L 5.0 (2.0–10.0) 6.0 (3.0–11.0) 7.0 (3.0–11.0) 6.0 (2.0–11.0)
HbA1c 48 (38–56) 46 (38–61) 50 (41–66) 47 (36–60)
Glucose, mmol/L 6.5 (5.1–8.0) 6.2 (5.5–8.1) 6.2 (5.2–8.4) 6.8 (5.5–8.1)
BNP, ng/L 3130 (1678–9943) 3385 (1357–8944) 4253 (1483–15,112) 4072 (1443–14,744)
Frailty 4 (3–5) 4 (3–5) 4 (3–5) 5 (4–8)
HGS, kg 23 ± 10 22 ± 11 19 ± 10** 17 ± 9***
DT, score 1.0 (0–3.0) 2.5 (0–5.0)** 4.0 (1.5–6.0)* 5.0 (4.0–8.0)***
BP meds, % 67.4 50.3* 64.1 62.3
  1. Data expressed as number, percentage, mean ± standard deviation, or median (interquartile range). *p < 0.05, **p < 0.01, ***p < 0.001 vs quartile 1