Table 3 Effect of renal anemia by cinacalcet therapy

References

Viana et al. [21]

Battistella et al. [22]

Fusaro et al. [23]

Tanaka M et al. [4]

Number of patients

28 (M 12, F 16)

40 (M 21, F 19)

14 PD

18 HD

8 over-night HD

5(M 3, F 2)

1337 (M 800, F 537)

Years old

Not listed

54.6 ± 14.2

65.9 ± 14.11

58.88 ± 11.78

Used drugs and initial doses

Cinacalcet 30 mg/day

Cinacalcet 30 mg/day

Cinacalcet 212.6 ± 60 mg/week

Cinacalcet dose unknown

Baseline iPTH (pg/mL)

716.9 ± 471.6

198 (153, 248) pmol/L

605 ± 150

340.00 (223.00–506.60)

Changed PTH (pg/mL)

307 ± 220.3 (1Y)^※

124 (79, 178) (3M)

116 (64, 180) (6M)

66 (42–136) (12M)^※

405.11 ± 50 (1Y)^※

Not listed

Baseline Hb (g/dL)

11.88 ± 0.75

11.6 ± 1.3

11.24 ± 1.31

10.65 ± 1.09

Changed Hb (g/dL)

12.29 ± 0.98 (1Y)^※

11.8 ± 14 (3M)

12.1 ± 12 (6M)

11.6 ± 1.3 (12M)

12 ± 1.19 (1Y)

Initial concentrationx1.1 (6M)^※

Baseline ESA doses

Darbepoetin 0.042 μg/kg/ week/g/dL

Darbepoetin 40 (20, 60)/week

Darbepoetin 70 ± 26 μg/week

Not listed

Changed ESA doses

Darbepoetin 0.033 μg/kg /week/g/dL^※

30 (20, 60) (3M)

30 (14, 65) (6M)

24 (20, 56) (12M)^※

Darbepoetin 48 ± 24 μg/week^※

Not listed

Baseline vitamin D doses

Paricalcitol 7.2 ± 4.5 μg/week

Calcitriol 0.125 μg/day

Not listed

Not listed

Changed vitamin D doses

Paricalcitol 6.0 ± 4.1 μg/week^※

Calcitriol 0.25 μg/day

Not listed

Not listed