Skip to main content

Table 2 Serum lactate concentration and PaO2/FiO2 ratio

From: Effects of prolonged direct hemoperfusion using a polymyxin B immobilized fiber cartridge on interleukin-6 concentration in patients with septic shock: a prospective exploratory trial

  PMX-DHP-2 h (n = 7) PMX-DHP-12 h (n = 16) P value
Serum lactate concentration, mmol/l    0.53
 0 h (baseline), N 7 16  
 median (IQR) 4.3 (1.3–6.0) 2.9 (1.3–6.7)  
 2 h, N 7 16  
 median (IQR) 2.9 (1.4–6.1) 3.2 (1.7–6.0)  
 5 h, N 6 14  
 median (IQR) 2.0 (1.5–6.2) 2.6 (1.6–4.0)  
 8 h, N 7 15  
 median (IQR) 1.8 (1.6–4.0) 2.9 (1.9–3.6)  
 12 h, N 7 14  
 median (IQR) 1.5 (1.2–2.7) 2.6 (1.7–3.7)  
PaO2/FiO2 ratio    0.53
 0 h (baseline), N 7 15  
 mean ± SD 278 ± 138 260 ± 128  
 2 h, N 7 15  
 mean ± SD 287 ± 108 279 ± 124  
 5 h, N 6 13  
 mean ± SD 329 ± 109 283 ± 120  
 8 h, N 7 14  
 mean ± SD 310 ± 124 289 ± 108  
 12 h, N 7 14  
 mean ± SD 318 ± 94 281 ± 109  
  1. The two groups were compared using a two-way repeated measurements analysis of variance. Serum lactate and PaO2/FiO2 were measured just before starting PMX-DHP administration (0 h). Serum lactate concentration was transformed into the natural logarithm before it was included in the analysis
  2. PMX-DHP-2h polymyxin direct hemoperfusion for 2 h, PMX-DHP-12h polymyxin direct hemoperfusion for 12 h, IQR interquartile range, SD standard deviation