Table 3 Increases in hemoglobin levels immediately before the onset of adverse events
Types of AEs | Disease stage | Rate of increase in hemoglobin level immediately before onset of AEs (g/dL/week) | ||||
|---|---|---|---|---|---|---|
<− 0.5 | ≥ − 0.5 and < − 0.3 | ≥ − 0.3 and ≤ 0.3 | > 0.3 and ≤ 0.5 | > 0.5 | ||
Overall patients | ND | 161 | 370 | 1522 | 477 | 212 |
HD | 155 | 419 | 1367 | 423 | 119 | |
PD | 43 | 138 | 330 | 153 | 71 | |
All AEs | ND | 7 (4.34) | 3 (0.81) | 48 (3.15) | 2 (0.41) | 2 (0.94) |
HD | 1 (0.64) | 2 (0.47) | 64 (4.68) | 7 (1.65) | 1 (0.84) | |
PD | 1 (2.32) | 3 (2.17) | 14 (4.24) | 2 (1.30) | 0 (0.00) | |
Vascular access thrombosis | ND | – | – | 1 (0.06) | – | – |
HD | – | 1 (0.23) | 8 (0.58) | 1 (0.23) | – | |
PD | – | – | – | – | – | |
Hypertension | ND | – | – | 21 (1.37) | – | 1 (0.47) |
HD | – | 1 (0.23) | 28 (2.04) | 1 (0.23) | – | |
PD | – | 2 (1.44) | 8 (2.42) | 2 (1.30) | – | |
Cardiovascular disease | ND | 4 (2.48) | 2 (0.54) | 21 (1.37) | 2 (0.41) | 1 (0.47) |
HD | 1 (0.64) | – | 15 (1.09) | 2 (0.47) | 1 (0.84) | |
PD | – | 1 (0.72) | 6 (1.81) | – | – | |
Cerebral hemorrhage | ND | 1 (0.62) | 1 (0.27) | 3 (0.19) | – | – |
HD | – | – | 7 (0.51) | 2 (0.47) | – | |
PD | – | – | 1 (0.30) | – | – | |
Thromboembolism | ND | 2 (1.24) | – | 5 (0.32) | – | – |
HD | – | 1 (0.23) | 22 (1.60) | 3 (0.70) | – | |
PD | 1 (2.32) | – | 1 (0.30) | – | – | |