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Table 5 Anemia response rate

From: Long-term safety and effectiveness of a continuous erythropoietin receptor activator (CERA) in patients with renal anemia: a prospective, observational, multicenter study

  ND HD PD
Treatment-naïve patients
N 678 111 66
 Response rate, n (%; 95% CI) 441 (65.04; 61.32–68.63) 60 (54.05; 44.33–63.55) 51 (77.27; 65.30–86.68)
 No effect, n (%) 237 (34.95) 51 (45.94) 15 (22.72)
Patients switched from EPO
N 160 399 20
 Response rate, n (%; 95% CI) 109 (68.12; 60.30–75.25) 279 (69.92; 65.16–74.38) 12 (60.00; 36.05–80.88)
 No effect, n (%) 51 (31.87) 120 (30.07) 8 (40.00)
Patients switched from DA
N 265 383 146
 Response rate, n (%; 95% CI) 162 (61.13; 54.97–67.03) 256 (66.84; 61.87–71.53) 99 (67.80; 59.58–75.29)
 No effect, n (%) 103 (38.86) 127 (33.15) 47 (32.19)
  1. Effectiveness: cases in which Hb levels reached ≥ 10.0 g/dL, and Hb levels increased by ≥ 1.0 g/dL until week 24
  2. Effectiveness: cases in which Hb levels were maintained within a range between 10.0 to 12.0 g/dL at week 48
  3. DA darbepoetin alfa, EPO erythropoietin, Hb hemoglobin, HD hemodialysis, ND not on dialysis, PD peritoneal dialysis