Skip to main content

Table 4 Summary of findings

From: Comparison of peritoneal dialysis and hemodialysis as first renal replacement therapy in patients with end-stage renal disease and diabetes: a systematic review

Peritoneal dialysis compared to hemodialysis for first renal replacement therapy in end-stage renal disease patients with diabetes
Patient or population: end-stage renal disease patients with diabetes considering renal replacement therapy
Setting: all settings
Intervention: peritoneal dialysis
Comparison: hemodialysis
Outcomes Impact No. of participants (studies) Certainty of the evidence (GRADE)
New-onset cardiovascular disease Two studies investigated new-onset cardiovascular disease among diabetic patients undergoing PD and HD. The differences in incidence favored HD in both studies. 22,656 (2 observational studies)
Very lowa,b
New-onset infectious disease—not reported  
Residual renal function—not reported  
Glycemic control—not reported  
*Risk in the intervention group (and 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and 95% CI).
CI: confidence interval
   
GRADE Working Group grades of evidence
High certainty: We are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: We are moderately confident in the effect estimate. The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: Our confidence in the effect estimate is limited. The true effect may be substantially different from the estimate of the effect.
Very low certainty: We have very little confidence in the effect estimate. The true effect is likely to be substantially different from the estimate of effect.
   
  1. aStudy limitations: failure to adequately control confounding factors and incomplete or inadequately short follow-up
  2. bSubstantial heterogeneity of results
  3. The English in this document has been checked by at least two professional editors, both native speakers of English. For a certificate, please see: http://www.textcheck.com/certificate/CnZ34r